Josh is jazzed at the prospect of meeting his TV idol when Drake gets tickets to “Oprah” for his birthday, but delight turns to dismay in the studio parking lot.

Drake e Josh sono due ragazzi dalle personalità molto diverse tra loro. Il fatto di andare alla stessa scuola sembra essere l'unica cosa che hanno realmente in comune. Ma sta per accadere qualcosa che li avvicinerà molto: stanno infatti per diventare fratellastri... e anche compagni di stanza.

Drake and Josh are on their way to a family wedding in their car. Unexpectedly and in the middle of nowhere, the car breaks down. This wouldn't be much of a problem, if it weren't for the fact that they're the ones bringing the cake to the reception.

Mindy tells Josh that she loves him and Josh slams the door in her face and runs to Drake, but Drake tells Josh that she is just trying to distract him so she can win the Science Fair.

Drake teases Josh that he can't get girls. So, Drake and Josh make a bet to see how many girls each of them can date in just one week. The rules are, every date must last at least one hour, you can't date someone you already know, and you can't date the same person twice.

Drake and Josh meet, "The Great Doheny", and find out that he relies on his new friends a little too much because he has lost everything including his career. In an attempt to get his career back for him, Drake and Josh find themselves in a tough situation.

Drake and Josh enter a "Pump My Room" contest to try and redecorate the living room as an anniversary gift for their parents. When they come back to the house they realize that everything is gone. To get the furniture and everything else back, Drake and Josh get a job at a sushi factory, but come home to see that everything is back.

The whole gang has gathered at Drake and Josh's house before Drake's big concert, but thanks to Walter's poor weather predictions they end up stuck in the house due to severe rain. Sure, it's raining outside, but the real storm for Drake to weather is when his new girlfriend meets his exes.

The boys are tired of sharing a ride and get money to buy a car, but all goes bananas when Drake buys an orangutan named Bobo instead. Soon they think they can make some money off their new friend, but things get hairy when they find out the man who purchased him may be an evil Doctor with unique.

Drake, Josh, and Megan must rebuild a tree house that they accidentally destroyed

Drake has taken advantage of Josh for the last time and Josh decides that he is done dealing with Drake. Drake says he's fine with this, but when Josh's life improves and Drake's goes down the drain this rocker begins crooning a different tune.

After accidentally punching Drake in school, Eric becomes very popular. Meanwhile, Josh thinks that Mindy has a new boyfriend.

Drake and Josh accidentally kill Megan's hamster and they think she is planning revenge.

After the boys get in trouble for using Fake ID's Audrey and Walter fear they will fall to a life of crime and sign them up for a “Steered Straight” program, but things start skidding out-of-control when a real criminal befriends them.

Megan's been extremely secretive and Drake and Josh investigate to find out what she's up to. The clues lead to a new boyfriend and all seems wonderful until they find out Megan's new beau may be trouble.

The most popular kid in school is throwing what may be the greatest sixteenth party ever, but Drake and Josh may be having cake for two after they get banned from the party.

It's the end of an era. After Josh ruins Drake's chances at having a hit song in the Superbowl, the boys must find a way to make things right.

It's the end of an era. After Josh ruins Drake's chances at having a hit song in the Superbowl, the boys must find a way to make things right.

Drake wins a free skydive off a helicopter and sets off to do it despite his parents' wishes. Josh, being the good brother he is, tries to stop him, but ends up going along for the ride. This fun time in the sky becomes a true downer when they accidentally lose their pilot and things start spinning out of control.

Josh decides to enter a local dance contest, but when Drake realizes he's going to fail gym, he has to enter in order to receive high school credit. So he steals Josh's dance partner, and that's when things start to go wrong.