When Piper contracts a life-threatening tropical virus that leaves her in intensive care, and to try to save her life, Prue and Phoebe cast an 'awakening' spell. However, since the spell was used for personal gain, the sisters can no longer sleep, and Piper's sickness spreads into an epidemic as a direct consequence. Meanwhile, Prue quits her job at Bucklands and Phoebe enrolls in university.

On Halloween, the sisters are pulled back in time to the 1600's to save a witch and her soon-to-be-born child from the hands of an evil witch who wants to raise the child evil. The sisters later discover that this situation may have more personal implications than they first imagined.

Cole poses as Belthazar to infiltrate an internet organization run by evil, that plans on controlling the world's information flow on the internet. Meanwhile, the sisters must vanquish the warlock posing as the company's manager without exposing Cole's role in the situation.