谁说超人只能是男人？曾经任职于银行的女强人——梁巧芝（蔡少芬 饰）因为一次意外，成为了外表火热、力大无穷、上天入地、无所不能的女超人。在变身成为女超人之前的巧芝是个对自己和他人要求极高，颇自负的女性，过了三十岁依然没有结婚，只因为眼界太高。 　　成为了女超人后，巧芝的异性缘也开始有所好转，先后邂逅了三大型男。型男一：整形医师简明轩（陈豪 饰）性格浪漫，非常会讨女性欢心，但过于执着黄金比例，让巧芝好不受打击；型男二：警界强人杨浩然（黄德斌 饰），性格豪爽，具有大男子主义，因为一次意外被作为女超人的巧芝所救，伤了其自尊心，因此一直在追逐着女超人；型男三：曾经的穷小子后来的富豪之子徐永晖（曹永廉 饰），一直痴心于巧芝的他却在身份变后性格也大变……无所不能的超人却无法抉择对象，最终的结果又是如何呢？

Fly With Me is an TVB modern comedy-action series. Leung Hau-Chi or Yvonne (Ada Choi) is a typical career woman in her 30s - fussy, arrogant and easily irritated by the sight of beautiful young women. Desperate for love and for something exciting to happen in her life, Chi is miserable and begins to despair when she abruptly transforms into a superwoman of incredible charm and strength.

With each new amazing power, Chi uses her extraordinary powers to fight for justice, help the weak, and go on remarkable adventures. On the way, she meets three kindhearted men: Yeung Ho-Yin (Kenny Wong), a brave but traditional policeman; Tsu Wing-Fai (Raymond Cho), a good-natured self-made businessman; and Kan Ming-Hin (Moses Chan), a genius plastic surgeon. To complicate matters, Hin happens to be in love with both Chi and her superwoman alter ego. Despite having superpowers, Chi has no idea how to find her true love.