Hank embarks on a fresh start with his medical practice and separates from his brother Evan, who also starts his own venture. As Divya attempts to reconcile the brothers, HankMed teams up once more in the face of a Hampton's emergency.

When Jill’s chess-obsessed nephew gets kicked out of camp for fighting, Hank realizes Luke may be suffering from more than just teenage hormones. Evan courts a young, lonely heiress for his new client roster, and Divya – caught between the brothers -- faces an impossible choice.

Hank and Evan heatedly compete for a new business opportunity. Meanwhile, Divya attempts to covertly reconcile the brothers' differences.

Hank & Evan's father Eddie makes his return to the Hamptons and schemes to bring his boys back together. Hank has a new patient who is participating in a zombie race for charity. Evan also has a new patient, a retired biochemist with a possibly sinister past.

A matchmaker patient tries to setup Hank and Divya. Elsewhere. Evan attempts to get a handle on the overcrowded HankMed. Paige plans a party that spins out of control, and Boris protects his family.

Hank attends a secret meeting in Manhattan; Evan and Jeremiah treat an Internet entrepreneur; Divya reconciles with her father.

Hank and Divya treat a veterinarian; Evan and Paige help a friend deal with loss; Boris must make accommodations.

An undercover DEA agent believes she is suffering from meth toxicity.

HankMed treats a polo team owner; Divya struggles with dating; Evan worries about a meeting of the in-laws.

HankMed treats a pop star before her tour; Evan helps Paige prepare for school; Hank gets to know a local pediatrician; Divya becomes distracted.

Hank works to diagnose two seemingly unrelated illnesses; Evan supports Paige during a difficult time; Divya's new boyfriend turns to Jeremiah for help.

Hank must travel to help an injured Dmitry; Paige deals with the fallout from the secret.

Hank has a realization about his relationships; Divya's fling takes a surprising turn.

The long-planned nuptials of Evan and Paige are finally here but along with this anticipated event comes secrets from the past that are finally revealed and flashbacks.

Several months after the events of the explosive summer finale. With the Hamptons decked out for the holidays, Dr. Hank Lawson continues to treat his patients in very unexpected ways, but Hank's biggest challenge will be facing his own medical issues. As the wedding approaches, Evan and Hank head to Las Vegas for some bachelor party fun, while Paige and Divya travel out of town for her bachelorette party. And with a snowstorm descending on the Hamptons, Paige rapidly finds her dream wedding turning into a nightmare.