While preparing for a friend's birthday party, the girls recall past birthdays, including Rose's surprise birthday party for Dorothy, a surprise birthday party for Blanche and a memory of Sophia's birthday involving her late-husband Sal.

Sophia's latest get rich quick scheme prompts the girls to recall other various get rich quick schemes they've had over the years including, catering, a dance marathon and a memory of Sophia's from 1954.

While waiting for phone calls from their children wishing them a happy Mother's day, the girls reminisce about past Mother's days.

The death of a close friend, Esther Weinstock, brings Sophia face to face with Esther's husband a man whom she vowed never to speak to again due to things that happened in the past. However, when Dorothy prompts them to make up they get a little to close and wind up in bed together. Soon after, they announce their engagement, something that Dorothy is totally against. Meanwhile, Blanche and Rose begin a Elvis Presley fan club.

It's Valentine's Day, and the girls are all excited until each one of their dates cancel at the last minute. This leaves them to reminisce about Valentine's Day past.

Dorothy becomes alarmed when Sophia forgets the date of her wedding anniversary. This leads Dorothy to face the fact that Sophia is becoming more and more forgetful with age. After visiting a doctor, Sophia decides to regain some of the memories she has lost and decides to take a trip to Brooklyn and their old apartment.

Sophia has an after-life experience, seeing her late husband in heaven, while choking on a piece of candy. Meanwhile, Blanche is distraught over the demolition of her grandmother's plantation, so the girls travel to Atlanta. Once there, Blanche handcuffs herself to the radiator.