Steve must stop a group of government conspirators who have assembled an atomic bomb from stolen parts.

While scientist David Tate experiments in space with a serum designed to awaken cryogenically frozen patients, he is accidentally injected with too much serum. When the space capsule crashes, he begins terrorizing the countryside and Steve must hunt him down.

A plane carrying Steve, a senator, and the senator's aides crashes in the desert. Steve must lead the others to safety despite being blinded in the crash.

When the Prime Minister of a small country has a heart attack while negotiating a peace treaty with neighboring countries, she is selected to receive the first bionic heart. Steve is assigned to protect her while she is transported to the secret hospital where the procedure will take place.

When Steve discovers that there is another bionic man - Barney Hiller, a race car driver - he is assigned to help him adjust to his bionics.

A UFO carrying four anthropomorphic aliens seeking a new home on earth crashes into the ocean. The aliens manage to escape their lost vessel and swim ashore. Having witnessed the UFO’s flight, Steve Austin investigates a town close to the point of impact. Things quickly turn confrontational when physical contact between an alien and a human causes the alien to slowly die and the human to suffer radiation burns. Steve Austin befriends the aliens and attempts to assist the sole survivor in returning to her people before she dies. Despite astronomical odds, an impending rocket launch appears to be the only possible solution.

When Oscar disappears, Steve investigates a lead involving a government-operated gold mine.

While Steve is helping a science team place earthquake sensors on the ocean floor, their boat is notified that the nearby country of Santa Ventura has broken off diplomatic relations with the US. Before their boat can leave the area they are captured by a Venturan patrol boat and Steve must help the team to escape.

An electrical short in Steve Austin’s bionic wiring causes him to crash land a plane in Colorado. Suffering from complete amnesia, he is taken in by a psychologist who is operating a home for the mentally depressed. Some locals in the town of Broken Fork do not want this home for “crazy” people in their community, and use strong-arm tactics to force it to move. Steven Austin gets embroiled in the controversy, amazing both himself and all witnesses with his seemingly inexplicable superhuman strength. As he searches for his true identity, Oscar Goldman leads a team trying to find his forgetful friend before his faulty wiring becomes fatal.

When Steve jumps a 12 foot fence to fix a malfunctioning space capsule, a newswoman happens to get it on film. After her boss sees the footage he attempts to kidnap Steve so he can sell him to a foreign country.

Steve is assigned to protect Liza Leitman, an equestrian trying to make the Olympic team; also the creator of the cryptography code that links computers and secret communications world-wide.

Steve consoles a woman, with whom he was once romantically involved, after her husband apparently dies in a plane crash.

When a plane carrying an atomic warhead crashes on a South Pacific island, Steve is sent to retrieve it, but finds that an ex-Japanese Zero pilot, Kuroda, has taken it to his home. Steve must successfully navigate his way through the booby-traps and get the warhead before a rogue guerrilla group does.

Doctor Dolenz returns and kidnaps Oscar, replacing him with a lookalike robot in an attempt to steal the formula for a new energy source.

The last known golden cougar is on the verge of being hunted down by local ranchers trying to stop their livestock from being killed. Steve's friend, and a local rancher, asks Steve to help him save the cougar from extinction.

While Steve Austin is on a one week fishing vacation, a Steve Austin look-alike shows up at Oscar Goldman’s office claiming that he decided to cut his vacation short. He secretly takes photographs of the Omega Project files, which are turned over to a middleman named Breezy. The real Steve Austin returns just in time to catch his double getting a tour of the Omega Project facility. The impostor is hit by a car and killed in the ensuing pursuit. Steve Austin then poses as the impostor, a former boxer named John Dine who had his face surgically altered to resemble the bionic OSI agent. The search for the photographs eventually lands him in the ring of a crooked boxing promoter.

When Oscar discovers that the construction of a top secret laser is being duplicated, he suspects that Harry Green, the expert overseeing the project, is a traitor. However, Steve disagrees and believes that Green's thoughts are being monitored through ESP. He obtains the help of Audrey Moss, also gifted with ESP, to track down the spy.

Steve Austin buys a ranch in his hometown of Ojai, California. He reunites with childhood friend Jaime Sommers who is now a professional tennis player. They rekindle a brief childhood romance. Jaime Sommers is injured in a skydiving accident when her parachute collapses toward the end of a jump. Her right arm, right ear, and both legs are severely injured. With Jaime’s life in peril, Steve Austin persuades a reluctant Oscar Goldman to fit her with bionics. Although skeptical at first, Jaime Sommers quickly acclimates to her mechanized components. The bond deepens between the two bionic humans. Steve Austin proposes marriage to Jaime Sommers, and she accepts.

While Steve Austin and Jaime Sommers plan their wedding, Oscar Goldman submits his bill for making Jaime Sommers a bionic woman: She is to go on her first assignment with her fiancé to switch a flawed U.S. $20 bill printing plate for a perfect copy in the possession of a foreign counterfeiter named Joseph Ronaugh. Steve Austin vehemently objects, but Jaime Sommers acknowledges her debt and agrees. The two succeed in their mission despite a malfunction in Jaime Sommer’s bionic arm which nearly causes it to fail. It is soon discovered that her body is rejecting the bionics. Dr. Rudy Wells conducts an emergency surgery to no avail. Jaime Sommers dies.

Revolutionaries kidnap the wife of the US Ambassador to the nation of Balinderry. In exchange for her release, the revolutionaries want their imprisoned fellow revolutionaries freed. With the help of Julia Flood, his liaison with the kidnappers, Steve attempts to rescue the ambassador's wife.

Steve is arrested when an assassin he helped send to prison seeks revenge by framing him for murder. Steve escapes from the police and must find the assassin before the police find Steve. Lee Majors plays a comic bit part as an elderly Electrical Store Clerk credited as L Majors.