Melinda Gordon just got married; during the dinner she sees something being drawn on the window and she knows it's a ghost. But for the first time, the ghost comes inside her house and that unsettles her. Despite being afraid, she tries to help him reunite with his family and pass along the message he needs her to say.

A boy who was killed in a collision with a train wants Melinda's help to ensure his mother that his death was not caused by her.

The identical twin sister of a teenage girl requests Melinda to help her apologize to her sister who is a psychiatric patient.

A man killed in a biking accident seeks Melinda's help to save his fiance's life and finding out who received his heart afterwards.

Melinda encounters the ghosts of three boys who died in the fire of an orphanage. They must cross over prior to the demolition of the building holding them inside.

Melinda helps an angry teenage ghost and discovers the secret that is likely to shake up the ones left behind by him.

In a hospital, Melinda encounters a woman who wants to determine what caused her death during a surgery.

An evil spirit is haunting Jim, causing him to begin doubting his sanity. Melinda must help this spirit, even though he is dangerous, in order to help Jim. .

The spirit of the mother of a teenage boy attempts to communicate with her son via white noise. Melinda must find a way to get her messages across.

A ghost of a bride who didn't make it through her wedding night is back with a vengeance haunting her husbands new fiancée to the point of her leaving him at the alter.

The dead mother of a boxer requests Melinda to assist in getting her son back together with his father. The son is furious because his father caused him not to be able to spent time with his dying mother.

After a stand-up comedian commits suicide, he's left in between worlds. Melinda tries to help him find closure.

The ghost of an elderly man suspects Melinda's new neighbor of killing his granddaughter.

A hanged man's ghost follows Melinda home from a macabre art installation, haunting her into contacting his troubled daughter. A woman sues Melinda's paramedic husband, claiming he further injured her whilst performing life-saving CPR.

Melinda is forced to remember how her relationship with her mother became strained after Melinda’s first ghost emerges. Melinda’s mother could not understand how to deal with Melinda’s gift. Melinda must reunite with her mother to help the ghost.

Andrea’s friend has gone missing during a hike and Melinda’s called in so she can use her abilities to find him.

Melinda comes across the spirit of an infuriated young boy, who's terrorizing his mother and baby sister.

When a traveling circus arrives, Melinda meets the bitter ghost of a magician who accuses his envious brother of his death, deemed to have been accidental.

Melinda must help the ghost of an African-American man who had been attacked and killed by a white co-worker in the 1970's. The ghost is haunting the prosecutor who had enough evidence but still failed to file charges against the white co-worker. Melinda tries to help the ghost find justice and help his son to change his racist views before they're passed on to the next generation.

Melinda experiences a sense of dread when she realizes that a plane is going to crash when the spirits of the pilot and flight attendant contact her.

After a jetliner crashes Melinda faces the overwhelming task of helping hundreds of passengers crossover. While Melinda faces this task she finds that the “Wide Brim Man” is working against her. Melinda must also try to work with the crash investigators who are trying to find out how Melinda knew that the plane was going to crash.