In the season two premiere, we pick up right where we left off. MacPherson has blown Artie to smithereens, and disappeared. Is Leena really a traitor? Where has Claudia gone? How will Pete, Myka and the Warehouse fare without Artie? What other havoc did MacPherson wreak when he was alone in the Warehouse? And is there yet a new villain on the horizon?

A super-powered vigilante is at large in Detroit, and the agents try to track down the person responsible. Meanwhile, things between Leena and Claudia are still tense, and Artie is haunted by the spirit of his dead friend.

When an artifact meant for the Warehouse turns up in the small town next door, the team finds themselves in the middle of a B-movie meltdown complete with cowboys, gladiators, sci-fi robots and beach storming marines. Their only chance of survival rests with the man who invented television, Philo T. Farnsworth.

When young super models rapidly age 50 years overnight, Pete and Myka go undercover in the glam world of high fashion to discover who – and what – is behind the transformations.

Douglas Fargo of Eureka's Global Dynamics is sent to Warehouse 13 to help update its aging computer system. This triggers a seemingly sentient computer virus that sends the Warehouse into lockdown and traps the team inside.

Mrs. Frederick secretly recruits Pete to find a mole within the organization who is buying artifacts. However, when the mole finds out, they go after those closest to Pete.

The agents hope to spend a weekend relaxing until an artifact gets in the way.

Someone is using Artie's artifacts to commit a series of murders.

Pete and Myka use H.G. Wells's time machine to travel back to 1961.

When Mrs. Frederic is stricken ill, the agents must search for a cure before it's too late. Their quest takes them to Egypt and the long-lost Warehouse 2.

The team tries to track down their rogue member, and discover the artifact they have is unexpectedly powerful. Meanwhile, Claudia wonders about her future with the Warehouse team and Pete must choose between Kelly and the mission.

As the Warehouse team prepares to celebrate the holidays in snowy South Dakota, Pete and Myka are called upon to hunt down a malevolent Santa Claus. Meanwhile, in time for Hanukkah, Artie and his estranged father, Isadore Weisfelt reunite after 30 years.