Echo is one of the "Actives" in the elite and illegal Dollhouse. Through different personality downloads, she plays the role of a lovestruck girl on a romantic weekend, and then a ruthlessly efficient kidnapping negotiator. FBI Agent Paul Ballard is struggling with his assignment to uncover information on the Dollhouse.

Echo becomes the female counterpart to an outdoorsman; Agent Ballard is encouraged when he receives a clue to Echo's true identity.

Echo becomes a backup singer to watch out for a female singing sensation with a very overzealous fan. Agent Ballard's investigation takes a turn for the worse.

Echo becomes an expert safe-cracker, and an invaluable piece of art is stolen from her on the engagement, forcing Sierra to take on a familiar persona. Agent Ballard gives Lubov an ultimatum, and Adelle confides shocking information to Topher.

Echo becomes the perfect wife for a lonely internet mogul, and Sierra's attacker is revealed. Meanwhile, Mellie's life is in danger and Agent Ballard's investigation takes a surprising turn when he comes face-to-face and goes fist-to-fist with Echo for the first very time.

A deadly virus outbreak on a college campus sends Echo back to school where pieces of her past come into focus.

When Echo, Sierra and Victor awaken in the Dollhouse with most of their original personalities and memories intact, Echo leads the charge to free the Actives from their apparent captivity and escape the Dollhouse forever. Meanwhile, Ballard discovers the Dollhouse is closer than he thinks.

When a traitor is discovered inside the Dollhouse, Echo and Sierra are programmed as spy hunters to uncover the culprit. Meanwhile, Ballard receives surprising news from Mellie, and Adelle harbors a secret.

When Adelle’s wealthy friend is murdered, Adelle imprints Echo with the woman’s memories and personality to solve the case. Ballard looks into Mellie’s past, and Topher secretly programs Sierra for an engagement.

Ballard’s investigation leads him to the agoraphobic designer of the Dollhouse (guest star Alan Tudyk), and the story of “Sleeping Beauty” foreshadows Echo’s future, while allowing her to help a young girl deal with her traumatic past. Adelle goes to the attic in search of answers, while Alpha reveals himself and sets his game in motion.

Alpha’s reign of terror continues as his obsession with Echo endangers Caroline’s survival. Ballard’s search for the Dollhouse comes to an end, forcing him to make a life-changing decision. Meanwhile, one Doll is permanently deactivated while another’s shocking past is revealed.