River: Won't stop. Won't ever stop. They'll just keep coming until they get back what you took. Two by two, hands of blue. Two by two, hands of blue."

River: "Two by two. Gloves of blue. Two by two. Gloves... blue... two"

"'The Hands of Blue' always appear in pairs, wearing blue gloves."

"Joss Whedon refers to them as 'the men with blue hands' and 'the blue-hands men'."

Who are they?

Children of the Academy who have been 'transformed'?

Psychics?

Cyborgs?

Androids?

Aliens?

Who do they work for?

The Alliance?

The Blue Sun Corporation?

"The two agents ('The Train Job', 'Ariel') that had been dispatched to pursue the Serenity and capture Simon and River Tam vanished between the last episode of Firefly, and the film Serenity, when the Operative had taken over their mission. So what happened to them, and what else can we gather from their appearances outside of the show?"

• What Happened to the "Hands of Blue"?