彼得和路易斯去度第二次蜜月，结果却与梅尔·吉布森作对；布莱恩和斯特威在克里斯被指控在学校舞会上饮酒后试图帮助他。

Chris为老师神魂颠倒。

Peter无意中救了人。

Meg唱起了蓝调。

Peter当场抓住了夸格麦尔。

Peter玩了一些头脑游戏。

Brian发现了小狗的爱情。

Peter得到了一张他无法填写的处方。

Lois黏糊糊的手指让她身陷囹圄。

Lois摆了一个姿势。

Peter发现Brian在面对女士时是条很好的狗。

Peter和朋友们的事情变得很棘手。

克里斯和彼得得了丛林热。

彼得向美国联邦通信委员会提出了一个不雅的建议。

布莱恩是校园里的大人物。

斯特威和彼得意识到世界很小。

彼得参与了胖子的战斗。

对格里芬一家来说，欢乐时光又回来了。

After Brian has a near-death experience in the hospital, he decides to lead a new life. He ends up getting a nightly singing gig with Frank Sinatra Jr., but his new lifestyle doesn't last very long. Meanwhile, Meg, after joining a new after-school group, pretends to be a lesbian.

At his high school reunion, Peter tries to impress his fellow classmates. When Peter, heading for the bathroom, charges through the crowd of people, impresses quarterback Tom Brady, who offers Peter a spot on the New England Patriots. Meanwhile, Brian owes Stewie money, after Stewie becomes a sports bookie.

When Peter wins a maid for a week as a prize on a game show, Quagmire gains an interest in her, and they eventually marry. Quagmire, stricken with his bachelor ways, tries to get out of the marriage. Meanwhile, Lois stops breast-feeding Stewie, who, as a result, goes through withdrawals.

Peter gets a vasectomy and loses all his sex drive. Lois begins to gain weight, and as a result, Peter's regains his interest in his wife. When Lois' habits get out of control, she has a heart attack. The surgeon must remove Lois' fat to reach her heart, returning her to her normal weight. Meanwhile, Stewie's half-brother Bertram returns to confront him, where they have a war for control over the playground.

Meg becomes an intern for Mayor West. Brian, who is sure that the mayor is corrupt, tries to out him. Brian and Stewie, while undercover, discover that Meg is more than just an intern. Meanwhile, Peter and Lois go back to their folk singing days at a local talent show. When they begin using drugs, Chris stages an intervention.

After reading an erotic novel, Peter gets the idea to write one himself. Carter gets sued for publishing Peter's book on tape and loses all his money, where he is forced to become a middle-class citizen. Meanwhile, Stewie tries to train for the Olympics.

Brian's gay cousin Jasper visits the Griffin house and announces that he is engaged to his partner and wants to be married at their house. When Mayor West bans gay marriage in an effort to cover up and bring attention away from a scandal of his own, Brian resorts to hostile actions to try to change the Mayor's mind. Lois and Peter question their view towards gay marriage while Chris joins the "Young Republicans" Club to impress a girl.

Peter wants to top Joe, who just built a new home theater system, so he starts to build a multiplex in his backyard. In doing so, he discovers an Indian burial ground. He finds an Indian chief's skull and the Griffin house becomes haunted. Stewie gets sucked into the television and strange events follow as they try to get Stewie back from the poltergeist.

When burglars break into the house, the Griffins take cover in the attic where they discover Peter has built a 'panic room'. They go in it, and Peter tells them about his history. They send Meg for food but the burglars catch her. The rest of the Griffins stay behind and Peter accidentally floods the room and they're going to drown. Luckily Joe gets them out and we find out Meg has been accused of sexual harassment by the burglars.

After losing at a swim competition, Stewie trys to eliminate his rival by blowing up a lifeguard tower. His plan backfires though, and Stewie has a near death experience that seems to change him.

Stewie convinces Brian to go on a road trip with him to San Francisco to search for a man Stewie believes is his real father.

Stewie finds out that his life in the future is miserable. So he decides to go back in time and change events for the better.