Elenco Principal da Temporada 5

1. 

   Seth MacFarlane

   Stan Smith / Roger (voice)

2. 

   Wendy Schaal

   Francine Smith (voice)

3. 

   Rachael MacFarlane

   Hayley Smith (voice)

4. 

   Scott Grimes

   Steve Smith (voice)

5. 

   Dee Bradley Baker

   Klaus (voice)

Convidados Especiais 10

1. 

   Tim Dadabo

   Waiter (voice)

2. 

   J.K. Simmons

   Judge (voice)

3. 

   Paget Brewster

   Michelle (voice)

4. Steve Hely

   Kermit the Frog (voice)

5. 

   Shawn Michael Howard

   Chris the Homeless Guy (voice)

6. 

   Mike Barker

   Jesus (voice)

7. 

   John DiMaggio

   Bouncer / Holy Spirit (voice)

8. 

   Peter MacKenzie

   Surgeon (voice)

9. 

   Jane Lynch

   Doctor (voice)

10. 

    Chris Diamantopoulos

    St. Peter (voice)

Equipa Técnica 3