Meredith Grey and the team of doctors at Grey Sloan Memorial are faced with life-or-death decisions on a daily basis. They seek comfort from one another, and, at times, more than just friendship. Together they discover that neither medicine nor relationships can be defined in black and white.

The doctors at Grey Sloan Memorial vie for a new position. Meredith is seemingly distracted and struggles to stay focused, and Maggie finds herself the keeper of a big secret while Amelia and Owen try to figure out their relationship. Meanwhile, Jo and Alex's honeymoon doesn't go exactly as planned.

Catherine is in Los Angeles getting the new foundation ready and summons Meredith and Koracick to visit for a highly confidential consult. Meanwhile, one of the nurses is 28 weeks pregnant and collapses at the hospital while talking to Richard.

Meredith questions Link’s laid-back approach over a patient’s treatment. Maggie worries that Richard, Jackson and Catherine haven’t come to terms with Catherine’s diagnosis. Meanwhile, Deluca steps up in the O.R. when Owen faces a setback.

Amelia and Koracick tackle a daunting surgery on Catherine while Richard and Jackson hope for the best. Meanwhile, Richard urges Meredith to visit her father, Thatcher, before his time is up.

A patient gives Meredith some clarity on her dating situation around the holidays. The strain on Bailey and Ben’s marriage comes to a head. Meanwhile, Betty drops a bomb on Owen and Amelia.

When Jackson throws a party to celebrate Catherine’s surgery and those who worked to save her, literally nothing goes as planned. Meanwhile, Helen pays Alex and Jo a surprise visit.

Owen and Teddy have to deal with the surprise arrival of Megan Hunt, who knows nothing about their situation. Catherine preps for her first surgery back on a war veteran who’s not emotionally prepared for his procedure. Meredith worries about DeLuca operating alone with Richard.

Alex tries desperately to save his patient Gus while he waits for a severely agoraphobic blood donor to arrive from London. Jo reveals to Meredith why she’s been so down, while Catherine and Bailey hold a meeting to get down to the bottom of an insurance issue. Meanwhile, Maggie and Jackson go camping.

As fog begins to cover Seattle, the doctors of Grey Sloan navigate through personal complications. Meredith and Alex attempt to save Gus, while Levi talks some sense into a struggling Nico.

Meredith, Richard and Alex must deal with the consequences after Bailey fires them from Grey Sloan for insurance fraud. After disappearing in the fog, Jackson helps a man in a dangerous situation, as his relationship with Maggie comes to a new crossroad. Meanwhile, Tom gets new responsibilities at the hospital that throw the doctors for a loop.

Meredith has a court hearing after skipping out on community service, while Bailey and Jo have a patient that Jo realizes is from the treatment facility. Richard and Gemma grab breakfast together and things go awry.

Catherine is back in town and has no idea what’s been going on between Jackson and Maggie, while her relationship with Richard has become distant. Owen and Amelia treat a woman who fell in the basement and quickly realize that there is more to the story, and Maggie is shocked to learn about some of Richard’s relatives who are seeking help.

Jo becomes a safe haven volunteer and gets a call that a baby has been dropped off at Station 19. Meanwhile, Meredith moves forward with her life after facing the medical board. Jackson takes a big step in his budding romance with Vic, while Bailey and Amelia swap pregnancy updates.

Richard finds out Maggie quit Grey Sloan and is concerned about how she’s handling the death of her patient who was her estranged cousin. Bailey returns to work after taking some personal time off, although Koracick doesn’t make her first day as easy as she’d like. Meanwhile, Meredith thinks she might miss DeLuca, and Amelia has an update for Link on her pregnancy.

Jackson creates an uncomfortable situation when he invites new girlfriend, Vic, to what he thinks is Richard and Catherine’s anniversary celebration, only to discover the dinner was called for different reasons. Elsewhere, Levi brings Nico on a trip to visit an ailing family member.

Richard preps to present his PATH pen at the LA Surgical Innovation Conference but becomes distracted by his issues with Catherine. Maggie and Teddy run into people from their past at the same conference, while Hayes relives moments from when he met his late wife.

Owen and Link treat an older woman who wakes up from surgery and can’t stop singing, while Teddy helps Koracick stay afloat after an estranged loved one from his past comes to the hospital looking for help. Meredith, Bailey and Maggie focus their efforts on a difficult patient with a tricky diagnosis.

Link tries to convince Amelia to take it easy during the final stage of her pregnancy. Hayes asks Meredith a surprising question, and Owen makes a shocking discovery.

Bailey finds herself in the middle of an argument with patients' families as they await news about their children who were injured in a fire; Winston surprises Maggie; Amelia and Link try to have some fun as new parents.

As traumas and pressure mount, Grey Sloan doctors try to find a path forward, and Richard questions his faith. Meanwhile, Maggie gives Winston hospital privileges and they work together to treat an uneasy patient. Jo, Link and Jackson play an unconventional drinking game.

The hospital ventilator shortage has the doctors gravely concerned when both a mother and daughter are in critical condition with COVID and fighting over the last ventilator. Meanwhile, Hayes’ high-risk sister-in-law with multiple sclerosis ends up in the hospital with a kidney stone, and the sister house has a few more kids join it as Amelia plays babysitter for the day.

Maggie is preoccupied with Winston while trying to treat a patient wounded in the Seattle protests. Meanwhile, Levi is tested by an emergency, and the doctors struggle to treat a patient who doesn't believe in COVID.

Jackson pays a visit to his father that helps set him on the right path.

It’s wedding day for Maggie and Winston. Meanwhile, Meredith takes on a new role at the hospital, and Jo makes a life-changing decision.

Richard recruits Meredith and Bailey to help him launch a new program. Meanwhile, Addison’s patient has complications from a procedure, and Jo helps a woman who goes into premature labor.

Schmitt must face the Morbidity and Mortality conference. Meanwhile, Meredith convinces Nick to scrub in on a surgery in Seattle, and Jo faces her feelings.

While Richard ponders his surgical abilities, Jo is charmed by her patient’s brother. Elsewhere, Megan makes sure Teddy and Owen talk out their differences, and a pet python causes an uproar.

Bailey faces an unhappy Catherine who is facing audits for several of her Foundation hospitals. Meanwhile, Addison is back at Grey Sloan; tensions rise between Meredith and Richard, and Owen returns to work.

A former patient of Link’s, Simon, is in the ER with his pregnant wife; and Bailey receives an offer from Nick.

A dinner party is thrown at the sister house in Nick's honor. Meanwhile, Grey Sloan Memorial receives a victim of a brutal hate crime.

The blood shortage at Grey Sloan Memorial continues. Meanwhile, Meredith makes a risky decision regarding a patient, and Owen’s actions to help his fellow veterans come to light.

Bailey and Addison take a road trip to volunteer at a family planning center, but a patient’s ectopic pregnancy leads to complications. Elsewhere, the interns play detective about Lucas’ relationship with Amelia, and Meredith catches up with Jackson on a trip to Boston.

Catherine returns to Grey Sloan for a surgical case that makes Lucas and Blue queasy. Amelia treats a possible cancer patient with a family that’s a little too supportive. Owen takes his medical future into his own hands, much to Teddy’s surprise.

Addison makes a special appearance at Grey Sloan to welcome Bailey’s new OB/GYN trainees. Maggie’s lung transplant is derailed, and Nick bonds with Lucas — before the day takes a shocking turn.

With Levi’s help, a patient celebrates a milestone. Jo processes a difficult diagnosis, and Maggie and Winston decide their future.

Simone's wedding day arrives as Jo and Link's relationship hits a major turning point.

The attending surgeons fly to Boston, forcing a reunion between Nick and Meredith. Bailey gets a big surprise.

Meredith rethinks her plans. The interns are on thin ice following a patient's death. Simone and Lucas are immediately tested in an emergency. Richard confides in Bailey. Teddy's fate is revealed.

Meredith and Amelia work to secure funds for their research while Amelia finds herself at odds with a new attending. Levi runs into someone from his past, and Owen gives Winston advice. Lucas ditches Mika, forcing her to treat a patient alone.