Ben worries that a casual conversation with Derek could potentially cause issues for Bailey, Cristina turns to Shane as tension grows with Meredith, and April's upcoming wedding makes for an uncomfortable situation between Jackson and Stephanie. Meanwhile, Meredith plans a Thanksgiving dinner at her house.

As Derek prepares for his move to DC, Meredith keeps herself busy at the hospital. Meanwhile, Jackson and April deal with difficult news, and Arizona and Amelia discuss how to best approach Dr. Herman.

When one of Grey Sloan’s own lands in the hospital, Bailey tries to figure out what happened while the rest of the doctors jump in to help. Meredith juggles huge secrets that affect her relationships with Alex and Maggie. While Richard helps Jo with a big decision, April and Catherine clash over the new baby.

A difficult surgery brings back pivotal memories for Meredith, Richard, Owen and Stephanie, as they work together to save a life.

Alex returns to the hospital and discovers a lot has changed since he left. Meanwhile, Jo has to make a difficult decision on a case, and Arizona tries to distance herself from Eliza.

During presentations on Grey Sloan Surgical Innovation Prototypes Day, Arizona shares cookies from an appreciative patient that, unbeknownst to her, contain a special ingredient. Meanwhile, Catherine reveals shocking details to Jackson about his grandfather's past; and Jo steps in mid-operation on a major surgery.

The hospital brings in crisis management to help them sort out allegations against Harper Avery. Nurse Olivia shows up at Grey Sloan with her son, throwing Alex and Jo for a loop Arizona decides to spend more time with Sofia who is having a hard time at school.

One of Grey Sloan Memorial’s own is seriously injured, making the team reflect on what is truly important to them. Meanwhile, Nicole Herman pays a visit to Grey Sloan and talks to Arizona about an exciting opportunity.

Catherine is in Los Angeles getting the new foundation ready and summons Meredith and Koracick to visit for a highly confidential consult. Meanwhile, one of the nurses is 28 weeks pregnant and collapses at the hospital while talking to Richard.

Seattle is hit by a huge wind storm and Grey Sloan becomes inundated with patients. Alex and Jo are stuck at home and decide to make the best of it by having a second honeymoon, while Meredith confronts Richard about getting his life back on track. The winter finale.

When a trauma patient arrives at Grey Sloan, it forces Jo to confront her past. Meanwhile, Bailey and Ben have to talk to Tuck about dating.

Owen and Teddy have to deal with the surprise arrival of Megan Hunt, who knows nothing about their situation. Catherine preps for her first surgery back on a war veteran who’s not emotionally prepared for his procedure. Meredith worries about DeLuca operating alone with Richard.

Meredith debates how to handle an unexpected situation in her personal life, while Richard has an untimely reunion with an old friend. Jo has a hard time at work, and Owen tries therapy.

Meredith heads up a pro bono surgery day, but the overwhelming patient response causes her to struggle to keep things in order. DeLuca treats a teenage patient whom he suspects is in danger and desperately tries to get Bailey to support his theory.

The Grey Sloan doctors continue to face their new COVID-19 reality and deal with a familiar and stubborn patient. Koracick is put in charge of the interns who recently joined the hospital ranks and Link operates on a sex therapist. Elsewhere, Maggie finds comfort in Winston's virtual presence.

A bull rider shows up at Grey Sloan with severe injuries, forcing Maggie, Amelia, Owen and Blue to examine their own biases. Elsewhere, Simone can’t find anyone to be her maid of honor, and Mika takes drastic measures to pay down her student debt.