Pravidelné obsadenie série 4

1. 

   Jonny Lee Miller

   Sherlock Holmes

2. 

   Lucy Liuová

   Joan Watson

3. 

   Jon Michael Hill

   Marcus Bell

4. 

   Aidan Quinn

   Thomas Gregson

Hosťujúce hviezdy 12

1. 

   Troy Garity

   Lucas Bundsch

2. 

   Chris Bauer

   Detective Gerry Coventry

3. 

   Eric Sheffer Stevens

   Tim Spalding

4. 

   Dillan Arrick

   Jenna Lombard

5. 

   Charlotte Maier

   Cynthia Tilden

6. 

   Kate Cullen Roberts

   Kathy Spalding

7. Dee Pelletier

   Polygraph Examiner

8. 

   Kacie Sheik

   Receptionist

9. 

   Ryan McCarthy

   Sheriff's Officer

10. 

    Lucas Dixon

    Sheriff's Officer

11. 

    Marcus Callender

    Young Cop

12. 

    Howard W. Overshown

    Detective

Štáb 10