Pravidelné obsadenie série 6

1. 

   Hugh Laurie

   Gregory House

2. 

   Lisa Edelstein

   Lisa Cuddy

3. 

   Robert Sean Leonard

   James Wilson

4. 

   Omar Epps

   Eric Foreman

5. 

   Jennifer Morrison

   Allison Cameron

6. 

   Jesse Spencer

   Robert Chase

Hosťujúce hviezdy 15

1. 

   Eddie McClintock

   Coach Stahl

2. 

   Ben Jelen

   Dr. Roger Spain

3. 

   Shari Headley

   Dr. Arlene Marks

4. 

   Erin Foster

   Dr. Petra Gilmar

5. 

   Skye McCole Bartusiak

   Mary Carroll

6. 

   Dylan Kussman

   Mr. Carroll

7. 

   Kelly Kirklyn

   Mrs. Carroll

8. Diego Clare

   Dawson

9. 

   Tim Haldeman

   Mature Man

10. 

    Geraldine Singer

    Woman

11. 

    Mark Bloom

    Doctor

12. Eric Cazenave

    Doctor

13. 

    Lindsay Pulsipher

    Teammate

14. 

    Rhea Lando

    Teammate

15. 

    Stephanie Venditto

    Nurse Brenda Previn

Štáb 7