Bullock's vigilantism makes new enemies. Utter returns to Deadwood to say goodbye to an old friend. Teenage siblings arrive on a quest to find their father. Alma holds on to her late husband's claim despite another offer from Farnum.

A much-needed vaccine arrives in Deadwood. There are rumblings of a treaty with the Sioux. Swearengen is reluctant to accept advice from Farnum while Trixie is away. Alma reconsiders her plans for her gold claim. Stubbs learns an important lesson from Tolliver.