From the edge of the Milky Way, a winged creature named Rokan speeds toward Earth. Superman confronts the beast and realizes it’s Rokan, a beast from Krypton which was thought to be extinct and since Rokan is from Krypton she has the exact same powers as Superman. Escaping, the creature wreaks Havoc on Earth. The Super Friends attempt stop to stop Rokan by chasing her and her babies away with Kryptonite.

The Wonder Twins agree to help Exxor defeat Darkon, a conqueror who has taken over Exxor and made its inhabitants his slaves. With the Wonder Twins captured by Darkon, Batman & Robin must free the twin heroes as the other Super Friends tackle Darkon and his troopers.

While sailing with Captain Pierre Marcel, the Wonder Twins and Gleek get sucked in a whirlpool. After receiving a distress call from the Wonder Twins, the rest of the Super Friends search for the twins only to get pulled in the whirlpool themselves. They emerge in a Wonder Land that is below the Earth’s crust. The Super Friends must now search for the Wonder Twins and rescue them

Traveling from space, three pirate ships make their way towards Earth. When Captain Sinbad and his Space Pirate crew reach Earth they start stealing treasures from South America. After receiving a message on the Justice League Trouble Alert, Superman and Wonder Woman confronts Captain Sinbad and his Space Pirate crew. Captain Sinbad then hurls city buildings toward a mountain range allowing the pirates to escape the two Super Friends. The Super Friends regroup to strategize and later streak off to confront the Space Pirates. While trying to stop a Space Pirate boat Wonder Woman gets hit with a stun laser and taken captive aboard one of the ships. Meanwhile at the Hall of Justice, the JLA satellite monitor picked up Wonder Woman causing Zan to convince Jana to go after her. When Zan and Jana find Wonder Woman, they get trapped by Space Pirates and a mind controlled Wonder Woman and were made Sinbad’s slaves. Wonder Woman then sends a warning to the other Super Friends to leave the Space Pirates alone or they may never see the Wonder Twins again. Superman then disguises himself as Clark Kent to enter the Space Pirates’ ship and rescue Wonder Woman and the Wonder Twins.

Traveling from a distant corner of the universe, a fleet of unidentified ships head towards Earth to hypnotize all children and gather them to Monument Valley, AZ. The Super Friends start to take action after the Wonder Twins became hypnotized and a call from the Justice League trouble alert. After the Super Friends tried to stop children from entering a spaceship, a UFO arose to destroy a nearby city. Batman & Robin stayed with the children as Superman and Wonder Woman stopped the UFO and the disasters it caused only to get trapped inside the space craft as it heads to the Anti-Matter Universe. Meanwhile at the Hall of Justice, The Wonder Twins escape by using hypnotic mind control on Aquaman to release themselves. Batman & Robin arrive back at the Hall of Justice to stop a near power source over load and snap Aquaman out of a mindless slumber. The Super Friends must now rescue the cargo of children and the Wonder Twins from slavery by an evil genius on the Planet Nofan and bring them safely home to Earth.

In the remote heights of Transylvania's alps, Dracula awakes after a 100 year sleep. Dracula starts havoc by releasing a strange glowing powder that turns people into vampires. Meanwhile, Batman & Robin receive a distress call and speeds off to Transylvania. They search Dracula's castle only to get captured by Dracula himself. Later Wonder Woman and Aquaman arrived in Transylvania after the Wonder Twins reported it was taken over by bats only to be attacked by dozens of mindless vampires. Another report of vampire attacks was made and this time Superman went to Vienna to stop them. While in Vienna, Superman runs into Dracula, who was continuing his conquest, and gets turned into a vampire. Realizing Superman is under Dracula’s control, the Wonder Twins attempt to stop the victimized Man of Steel. Wonder Woman, Aquaman, Batman, and Robin all escape the face of danger only to find that Superman and the Wonder Twins have been turned into vampires and are turning nearly everyone else into vampires as well. The four Super Friends regroup at the Biological Research Center in Switzerland to find a way to reverse the affects the vampires have on people. They now must find a strange breed of South American bat in the Andes Mountains whose cave has gases that could reverse the vampire effect. It’s now up to the Super Friends to transform the vampires back to normal and figure out a way to stop Dracula.

After an experimental satellite from Kennedy Space Center falls back to Earth it breaks releasing deadly radioactive energy. The Super Friends then receive a distress call from the west coast saying Death Valley is being overrun by giant desert beasts. Wonder Woman and the Wonder Twins stay behind to check the Justice League computer for more information while the rest of the Super Friends head to Death Valley. At Death Valley they find wreckage and a man who says giant lizards had nearly destroyed the town. As Superman continues to search for the mysterious giant beast, he stumbles upon some mutated giant earthworms that he must save some teens from. As Aquaman, Batman, and Robin fight the beast creatures that attacked them, Wonder Woman finds out what happened via the Justice League computer and heads to NASA for more information. As Wonder Woman approaches the location of the downed satellite, the radiation turns her into a giant beast. As the Wonder Twins try to stop Wonder Woman’s destruction of a military base, the radiation genetically alters them into giant beasts. Meanwhile giant earthworms are digging holes into California's coast which will potentially sink. To save everyone the Super Friends must stop the creatures and turn them and the “Wonder” heroes back to normal.

Three Kryptonian villains from the Phantom Zone escape and expose Superman to Red Kryptonite causing him to age rapidly. The rest of the Super Friends get trapped by the villains and must now escape from the Phantom Zone. Meanwhile, the Justice League Computer tells Superman the only possible antidote for his rapid aging is Blue Kryptonite. Since Blue Kryptonite is harmful to Bizarro, it may have an opposite effect on Superman. Superman must take the Supermobile to go to the site where Krypton blew up and get the Blue Kryptonite in time to save the other Super Friends. Using the ray device the three villains stole from Superman, he sends the Kryptonian villains back to the Phantom Zone.

In this story the Super Friends have to stop an energy draining monster which exists on computer tape and can appear anywhere at anytime. Wonder Woman and Superman, during one scene, go undercover as a science expert and Clark Kent, in an attempt to learn how the energy creature can be destroyed. One of the scientists working in the lab turns out to be the culprit responsible for unleashing the energy creature. The story borrows heavily from the national headlines of the time during the concerns of a looming energy crisis.

The Super Friends must stop the plans of a conqueror named Torhana who seeks vengeance on the people of the surface world by freezing everything in his path. Torhana and his crew travel by ship, freezing oceans and continents and people...Aquaman uses his telepathy to summon sword-fish to cut him out of the ice and take him to Atlantis. Torhana and his crew appear to have the upper hand but by episode's end the Super Friends regroup and come up with a clever plan to melt all of the ice that's engulfed the planet. This is one of the few episodes in the series that features Aquaman at his usual base of operations in the comic books: the undersea city of Atlantis.

A crooked space circus proprietor, Zarnum, uses a device to turn protected animals that have been illegally captured into beasts to boost attendance at his space circus. Sensing that the Super Friends are onto his scheme he uses the device to change Wonder Woman, Aquaman, and the Wonder Twins into space creatures. It's up to the rest of the Super Friends to track down the elusive space circus, rescue the captive Super Friends, and bring an end to the poaching that's been taking place.

NOTE: Zarnum's name is loosely based on circus legend P.T. Barnum.

Batman and Robin head off to a planet named Texarkana after receiving a distress alert that a local villain, The Capricorn Kid, is terrorizing the planet. After defeating the Kid and putting him in jail the Kid vows revenge. He and his group of outlaws travel to Earth, break into the Hall of Justice, and plot their revenge on all the Super Friends. The Kid's group successfully places each of the Super Friends in dangerous situations and they deliberately force Batman and Robin into freeing each person...but the catch is that each trap is timed and the object of the game is to free all the Super Friends from the various traps before it's too late. In a show-down Batman and the Kid meet up in an old-fashioned shoot out.

At the start of the episode the Super Friends are involved in an intense outer space battle. Moments into the battle Wonder Woman gets a telepathic message from Aphrodite to help save the planet from a disturbance. Afterward all of the Super Friends show up and Aphrodite praises them on their great work and good will. An envious Hera gets into an argument with Aphrodite on Mount Olympus which triggers the wrath of Zeus. Hera criticizes Aphrodite for praising "mortals" such as the Super Friends and she suggests to Zeus that the Super Friends are not as powerful as Aphrodite claims. Zeus then creates a contest in which each of the Super Friends must do battle with mythological demons in an effort to prove they are worthy of Aphrodite's praise. Batman and Robin must battle a Sphinx and solve its riddle, Aquaman has to fight a demon that protects the golden fleece, Superman battles a minotaur, and Wonder Woman has to battle Medusa. The Wonder Twins get mixed up in all of this when they see Medusa in the shadows and mistake her for Wonder Woman...and once they look her in the eyes they turn to stone. Gleek manages to escape Medusa's clutches and ends up aiding Wonder Woman in removing Medusa's necklace. By episode's end the Super Friends prove to be worthy of Aphrodite's praise.

Aquaman is exposed to a radioactive substance that turns him into a prehistoric sea creature from which he evolved. In order to cure him, Superman and Wonder Woman, inside the Super Mobile, are shrunk down to microscopic size and sent within the creature's veins to attempt to give it another dose of radiation in the hopes that it will reverse the effects of the radiation and return Aquaman to normal. In the meantime the rest of the Super Friends have to do whatever they can to limit the creature's destructive nature all over the city.

The Super Friends are visited by Mr. Mxyzptlk who comes complete with a script for a movie that he wants the Super Friends to star in. The imp uses his 5th dimensional mind control to cause the Super Friends to act out the script...but Superman is not affected by the mind control but he nonetheless goes along with everything in an elaborate plot to trick Mxyzptlk into saying his last name backwards. In one scene a zombie Lois Lane shows up in a wedding dress wearing a kryptonite wedding ring.