The First iteration (1999-2001) was described as the "Dear Abby for the Hip-Hop Generation", with the series covering various topics and including interviews with celebrities and non-celebrities alike. The Second iteration (2013-2015) featured celebrity interviews, human interest stories, musical performances, and Queen Latifah's take on pop culture news. Latifah also ventured into communities across the country to share compelling stories, celebrate individuals who give back to their communities and delivers life-changing surprises.

Previously, a talk show with the exact same title aired from 1999 to 2001; however, the second iteration is not a revival of this older syndicated television production. Telepictures (1999-2001) / Sony Pictures Television (2013-205) with Flavor Unit and Overbrook.