Earth is losing to a superior foe, as the very survival of the planet lies within a message from a distant galax

The Earth Defense force mission is clear - take the newly rebuilt Yamato 148,000 light years to the planet Iscandar, to retrieve a machine called the Cosmo-Cleaner D which will save Earth from its irradiated state. But will the Gamilas stop them?

The Yamato tests out the Wave Motion Engine's warp capabilities, which will allow them to travel 148,000 light years to Iscandar and back in one year. But will the Gamilas stop them?

The Yamato is trapped by Jupiter's gravity.

The Yamato searches Saturn's moon, Titan, for a rare mineral.

The Yamato faces disaster on the planet Pluto.

The Yamato destroys the Reflective Satellite

Limping along, the Yamato comes up with a new defensive strategy.

The Yamato says goodbye to their families before leaving the solar system.

Gamilas Supreme Commander Desslar unveils a trap that will destroy the Yamato: space mines. But these mines have a sinister function..

Dessler prepares another trap for the Yamato: an energy net that captures them. The only way out is in the direction of a massive sun, as a huge secret is revealed that might affect the crew.

A Gamilas pilot is captured and the Yamato interrogates him, as Kodai personal tragedy comes into play.

Tensions mount on the Yamato as she is trapped in a space storm.

Desslar commissions Gamilas General and war hero Domel to defeat the Yamato. The Yamato travels near a galactic whirlpool, but as assist from afar saves their mission.

Analyzer and Yuki fly down to a planet looking for food for the crew, but are captured by the inhabitants. Analyzer reveals a secret to Yuki that will change both of them.

Gale, the general Domel replaced on Balan, devises a plan to destroy the Yamato. Captain Okita is critically ill, and Kodai steps into action.

The Yamato comes across a Gamilas fortress that emits Magnetron waves, which set vibrations into metals and rips them apart. Kodai and Sanada board the fortress using a new seamless plane that Sanada created. They destroy the base, and the Yamato flies on.

Chief Communcations Officer Aihara is worried about conditions on Earth. But what does he know that the crew doesn't?

The Yamato reaches planet Balan, the halfway point in their mission to Iscandar. But Domel is waiting on his base there, and springs a trap that might destroy both the Yamato AND the base...

Gamilas General Domel, pardoned for his failure at Balan, challenges the Yamato to one final battle.

The Yamato battles Domel for the last time.

The Yamto finally arrives at the Magellanic Cloud and "Iscandar"... but have they found their hope for survival, or their enemy's haven?

The Yamato fights on Gamilas, as the Yamato survival depends on wiping out an entire civilization.

The Yamato finally arrives at Iscandar.

The Yamato Returns Home! With the Cosmo Cleaner D, they are ready to save Earth. But one final battle may cost them a crew member closest to Kodai...