The comedian assists vet Gwen as she takes on the case of Staffordshire bull terrier Annie, who has a suspected broken leg and a mystery lump. In Carlisle, Inspector Sam tries to save the life of a severely beaten dog called Bruce.

At the Putney Animal Hospital, a Yorkshire terrier undergoes major surgery to resolve a limp, while an inspector helps a woman in the West Midlands who has taken on a lively puppy.

Herchy rescues a staffie dog from a tower block, with police warrant in hand. Nicky cannot find a kennel for an unhomed hound signed over by an owner to ill to care for him. Claire has a stray bulldog mystery to solve in Essex.

A second warrant is issued in the Accrington investigation to search another property, as new evidence emerges that more dogs may be in danger. Inspector Charlotte takes up the challenge of handrearing two abandoned day-old puppies called Doris and Dave.

Anthony refuses to be intimidated by an aggressive owner when he goes to rescue two dogs, one with a serious skin problem. Clare signs over a sweet Jack Russell that lives up to its name of Angel, while Herchy is called in to help an owner whose dogs have an uncharacteristic fight.

Anthony gets a report of a starving dog, but he gets a nasty sense of deja vu when he arrives at the address. Herchy finds that a very messy house poses a safety hazard to dogs Roxy and Rocky. Angellica Bell finds out what life is like for dogs on the street.

In Staffordshire, Inspector Charlotte is left reeling by a menagerie of animals including a fox, a snake, a lizard and two dogs. Kris tackles two dogs left in the care of a neglectful relative while the owner is away. Alan helps vet Imogen clean Sonny's teeth.