Big Girl's Blouse is an Australian skit program that aired in the mid-1990s on the Seven Network. The show was created by Gina Riley, Jane Turner and Magda Szubanski who all went on to star in Kath & Kim. There were four one-hour episodes, plus the pilot, which are usually shown as eight half-hour episodes. The phrase "Big Girl's Blouse" is a British English idiom meaning "ineffectual or weak, someone failing to show masculine strength or determination".

In Australia The Comedy Channel currently airs the series as part of their Aussie Gold block hosted by Frank Woodley. In America it occasionally appears on the Sundance Channel.

The show has been released in its entirety by Shock DVD in Australia.