Margie wants to have her portrait painted as a present for Vern's birthday. Short on money, she arranges to pretend to be the girlfriend of an artist to impress his friend and in exchange he will paint the portrait. Vern gets suspicious and, following Margie, thinks she is having an illicit affair.

Vern plans to do some business with the Dean at his college reunion, but Margie intends to teach him a lesson when she finds out he and his friends weren't quite as dignified in college as he had claimed.

Vern calls in sick so he can take the day off and go to the beach with Margie at her suggestion. Trouble arises when he runs into a client and, without realizing who she is, brags about being irresponsible.

Vern tells Margie he will take her to Hawaii if she can last through a Canadian hunting trip. He's convinced she won't be able to take it, but Margie outfoxes him by hiring three men to do all her work for her.

Vern tries to get Margie interested in writing, thinking it will keep her out of trouble. In order to research her book, Margie starts pretending she has amnesia and when the police get involved, its wall-to-wall trouble for everyone.

Margie asks Vern for a job at Honeywell & Todd, but Vern says no. When Margie's lookalike cousin arrives, Vern thinks its Margie in disguise and decides to get even.

Margie tries to convince Vern to be more aggressive with Mr. Honeywell by taking him to a phony seance in which Mrs. Odetts pretends to be a spirit giving him advice.

Vern and Mr. Honeywell make Margie believe she has a secret admirer to keep her from entering an auto race. When Margie tries to find out who the secret admirer is, Vern's new client gets involved.

Margie tries to help the daughter of Vern's new client. He doesn't know his daughter is married and has a baby, so Margie has to pretend the baby is hers.

Margie tries to help her neighbors repair their marriage by making the wife jealous, but Vern and Freddie end up thinking they are having an affair.

Vern always wins the annual fishing tournament and Mr. Honeywell offers Margie a mink coat if she will help him beat Vern.

Vern is the foreman on a jury that convicts a gangster. Worried about her father's safety, Margie sets a trap for what she thinks are the gangster's henchmen, but turn out to be a mild-mannered client and a private detective.

Margie invites Mr. Honeywell and a prospective client to dinner. She lets Freddie, who now has a job selling cookware, make the dinner. What she doesn't know is that Vern's client is a competitor of Freddie's company.

Vern doesn't want Margie to meet a client's son, so he sends her out of town and has Roberta pose as Margie. When a suspicious Margie returns, she catches on and then pretends to be her own imaginary sister, Helen.

Vern convinces Margie to break her date with a Marine to go out with a client's son. An angry Margie uses helium to inflate her dress so she will look fat. The plan backfires, however, when the client's son turns out to be a dreamboat.

The set and costumes used in the ""My Little Margie"" episode ""Margie's Millionth Member"" are from ""Rocky Jones Space Ranger"". Both sets and costumes were used at The Hal Roach Studios. The name of one of the cereal company owners is ""Mr.Crackie"".

Margie agrees to babysit for a chimpanzee that belongs to one of Vern's clients. Vern, not realizing who the chimp belongs to, pays Freddie to kidnap it. When Margie learns of the plan, she tells Freddie to go ahead with it to teach Vern a lesson.

Margie must pretend to be a birdwatching enthusiast in order to keep a client of Vern's around long enough to sign a new contract.

A misunderstanding over Mr. Honeywell's health leads to Vern being fired. Now Margie must scheme to get his job back.

At a health farm for wealthy women, Margie switches identity with a friend who wants to be sure her new boyfriend isn't after her money.

Vern tells Margie if one more thing goes wrong she won't get her trip to Sun Valley. Margie then gets into trouble when she tries to operate a broken elevator and ends up taking a fellow tenant on a wild ride. When the woman threatens to sue, Margie tries to keep the landlord from talking to Vern, by convincing Vern it is the middle of the night.

Margie, Vern and Mrs. Odetts go to Mexico to see a client and run into plenty of trouble and misunderstandings.

Freddie has a new job selling lipstick that lasts three months. When Margie messes up a demonstration Freddie was trying to give to Vern's new client, she must think of a way to correct the problem she has caused.

Margie and Vern babysit for client's grandson who happens to be an obnoxious brat. What Margie doesn't realize is that the old lady neighbor who is helping them amuse the child is actually a notorious thief.

Vern thinks his job is being taken over by an ambitious young man at Honeywell & Todd. The man is a big fan of murder mysteries, so Margie and Roberta set up a real mystery to try and trick him into leaving the company.

Margie decides she wants to live in a ground floor apartment and to convince Vern it is a good idea she makes him believe he walks in his sleep and it is dangerous for him to live on the tenth floor.

Mr. Honeywell makes Vern hire the daughter of a client to be his secretary. When the girl falls for Vern and wants to marry him, Margie tries to make her see how ridiculous the age difference is by dating the girl's aged father. The only problem is, the old man really falls for Margie.

To keep a new client away from Margie, Vern lies and says he has a son instead of a daughter. When the client wants to meet Vern's son, Margie disguises herself as a boy.

Margie's new boyfriend is a lawyer who convinces Margie Vern has no legal right to treat her like a child.

In order to breakup Margie and Freddie, Vern and Mr. Honeywell convince Freddie that Margie would like him better if he acted like a cave man. Margie discovers their plan and retaliates by pretending she loves the ""new Freddie"".

When Vern and Freddie are called to duty by the Navy, Margie ends up a stowaway on their ship.

Vern gets carried away with fencing lessons and neglects Roberta. Mr. Honeywell hires a Frenchman to make Vern jealous.

Convinced Mr. Honeywell would be a better boss if he were a married man, Margie gets him a date at a lonely hearts club. When the woman turns out to be a gold-digger, Mrs. Odetts and Margie pose as Mr. Honeywell's wife and daughter to get rid of her.

Margie is careless with her money, so Vern tries to teach her a lesson about financial management. Margie ends up thinking her father has gone broke and rents out their apartment to a couple of wrestlers.

Vern gets into trouble when he forgets his entry permit on a trip to South America and ends up tangling with a commander, unaware that he is the client he is there to sign.

Despite Vern's objections, Margie is determined to meet Vern's old fraternity brother, the Shah of Zena...even if it means sneaking into his hotel room.

When Margie accidentally breaks a set of antique bagpipes belonging to the head of a Scottish lodge, she tries to replace them with Mr. Honeywell's set.

Margie poses as a 12-year-old immigrant girl to help Mr. Todd out of a misunderstanding he is having with his wife over a check he wrote.