Supervillain M.O.D.O.K. runs his evil organization AIM into the ground and is forced to sell it to the tech company GRUMBL. As the megalomaniacal M.O.D.O.K. struggles to regain control of AIM he risks losing something even more important… his family!

In an effort to win back his wife Jodie, M.O.D.O.K. takes her traveling through time to a Third Eye Blind concert they missed years ago. However, things take a wrong turn when they get attacked by a college-aged M.O.D.O.K. who damages their time machine stranding them in the past.

M.O.D.O.K. drags along his kids, Melissa and Lou, to a GRUMBL leadership conference. Once there, he accidentally unleashes a hedonistic alien menace on the conference while trying to prove his leadership skills to his bosses and children.

M.O.D.O.K. is turned away by his world conquering peers and forced to slum it with some blue-collar street villains. He intends to use them for his own gains, but a wild night out on the town leads M.O.D.O.K. to something more valuable: adult friendship?

M.O.D.O.K. and Monica reluctantly team up to overthrow GRUMBL's control of AIM. Their “complicated” history threatens their mutual goals as they work through their grievances the only way they know how… a mad-scientist fight!

M.O.D.O.K. struggles to “normalize” his weird son Lou’s bar mitzvah planning. Lou flees to Asgard where he and M.O.D.O.K. find themselves on opposing sides of a mythological war that threatens to split the realm in two.

Jodie's celebrity is on the rise and she begins to date the superhero Wonder Man. At Jodie’s book release party, M.O.D.O.K. tries to win her back by provoking Wonder Man into attacking him. The debacle leads to unexpected repercussions.

The time travelling Young M.O.D.O.K. finally exacts his revenge by kidnapping the family and pitting them against each other in a twisted family therapy / battle to the death.

The family reunites for Lou’s bar mitzvah but the surprise return of a villain threatens M.O.D.O.K.’s past, present and future in the show’s season finale.