In West Virginia, Kimble arrives at a local coal mining town where he is roughed up by the redneck locals, and then chased by a sheriff's posse. Hiding in the mountains, Kimble meets Cassie, a young woman living in a remote cabin with her grandmother. Cassie tells Kimble she get him to safety because she knows the area, when she is really wanting to keep him around for her own selfish reasons. Meanwhile, Gerard flies to West Virginia after learning from the sheriff that Kimble has been spotted in the area and teams up with the posse to try to find Kimble.

While working as a hotel lifeguard in Reno, Nevada, Kimble is caught in the middle of a feud between the hotel owner Dan Polichek, and his spoiled and rambunctious teenage daughter Christine. 'Chris' belives her father drove away her mother whom commited suicide years ago and she sets out to disgrace Mr. Polichek by provking bar fights, humiliating herself, and goes too far when she pretends to be engaging herself in an affair with the reluctant Kimble.

Jane Washburn, an undercover policewoman, witnesses three youths beat up and rob Kimble. She attends to him, but becomes suspicious after he declines to report his mugging to the police. So, she handcuffs herself to Kimble to arrest him, but he manages to flee the area with her. After Jane sprains her ankle after hopping off a freight train, they break into an abandoned farm house so Kimble can attend to her, as well as saw off the handcuffs. But the family who lives there soon returns and Kimble is held at gunpoint by the domineering and rabid patriarch of the family.

At a carnival, Kimble meets Tina Anderson, an attractive young woman whom helps him get a job and introduces him to her uncle Harry, whom is a retired police detective. But Harry soon recognizes Kimble and tries to arrest him. Tina helps Kimble get away and wants to run off with him, but he refues. Tina, whom is revealed to be an obsessed sociopath, plots to betray Kimble for him refusing her advances.

After learning of the death of his father, Kimble contacts Donna and her husband Len Taft and wants to meet with them. Donna and Len drive to Fort Wayne, Indiana and check into a hotel under assumed names. But their rendezvous is threatned by Mike Ballinger, the former prosecuting attorney at Kimble's trial, who recognizes them and calls on Gerard to set up a trap.

Kimble is working as the ""general factotum"" in a swank Beverly Hills hotel on Sunset Blvd. An undercover policeman, named Fred Bragin, checks into the hotel to survey Eddie Slade, a notorious mob bookie. When Slade leaves town for a few days to sort out some business of his, his girlfriend, Penelope, stays behind while Bragin focuses his surveillance on her. Penelope meets and turns to Kimble for help in mingling with the wealthy in-crowd of the hotel residents in which Kimble agrees to tutor her on the find art of socializing, manners, and better increasing her vocabulary.

While hopping a freight train, Kimble meets a wounded criminal who demands to take him to a rendezvous point in the hills of Southern California. Kimble reluctantly does which is an isolated cabin in the deep woods where they are joined by three more men whom happen to be robbers of an armored car who demand from the criminal their loot. Not believing their accomplice's true story that he lost the money when it fell off the train due to his gunshot injury, the three robbers hold Kimble, a widow named Laura Craig, as well as a park ranger who happens by, while torturing the man for the location of the money.