Presley was living with a boyfriend who didn't make any money to help support them. She started stripping for extra money. This angered her boyfriend so she then sought out an agent on-line to do pornography. Her first role was in Just Over Eighteen 10 from Red Light District Video. She performed in 70 pornographic film scenes over the next eight months, many of which included anal scenes. In late-2004, she signed an exclusive, three-year contract with porn production studio Digital Playground. Presley claims she first became involved in pornography as revenge against her ex-boyfriend. Teagan has also appeared on mainstream television. In 2004, she appeared on The Howard Stern Show with fellow starlet Cytherea. Both served on a panel to judge girls who wanted to enter the pornography industry. In 2005 she appeared on the HBO show Entourage as a member of the "Pussy Patrol" in Season 2, Episode 9, "I Love You Too".

Teagan Presley left Digital Playground to start her own web site and production company with her husband, adult performer Tyler Durden (AKA Tyler Wood). She complained that Digital Playground was not allowing her to perform for her new company. However, Digital Playground refuted the complaint and said that Teagan was free to work as lawyers were resolving her contract status. While there were reports that her surname "Presley" was owned by the studio Digital Playground, a representative of the studio has denied those reports as false.In October 2008, she was invited by Digital Playground to host the red carpet at the premiere of Pirates II: Stagnetti's Revenge, a film produced by the firm. She is also seen on the cover of Temptress magazine in the unrated version of the movie Superbad. Teagan was also interviewed by Bush League TV for their short internet video "Bush League 101: How to Break Into the Porn Business." In July 2008, she announced that she had her breast implants replaced and that she would be auctioning them on eBay, with 20% of the proceeds going to Susan G. Komen for the Cure; she also announced that she would stop performing boy/girl sex scenes. The remainder of the proceeds were to be used to fund her divorce and custody cases.

In September 2008, in partnership with Rock Star Diversified Entertainment and St Louis Missouri based WAZUPSTL Web Promotions & Design, Presley helped create the first Blu-ray-centric adult review site AdultBluReview.com, where Teagan herself and other adult starlets review adult Blu-ray titles. Official AVN Press Release In October 2008, Presley was named Best Feature Dancer by Nightmoves magazine. In November 2008, she was named the Penthouse Pet of the Month for January 2009. Presley and her boyfriend Josh Lehman launched their own studio called SkinWorxxx in early 2009, with their first production called The Search for Sun Goddess XXX. In November 2009, Presley signed with Adam and Eve Pictures as an exclusive performer, with her first film to be Bree & Teagan, appearing with Bree Olson. In 2010, she was named by Maxim as one of the 12 top female stars in porn.