皮卡出生于英国切斯特，是黛西（原名威廉姆斯）和讲师埃里克·皮卡普的儿子。[1] 皮卡在切斯特国王学校接受教育，在伦敦皇家戏剧艺术学院（RADA）接受培训，并成为RADA的准会员。

他的电视工作始于 1964 年《神秘博士》第二季的一集，为此他获得了 30 英镑的报酬。皮卡在皇家国家剧院与劳伦斯·奥利维尔（Laurence Olivier）合作，最著名的是《三姐妹》和《漫长的夜晚之旅》。1973年，他出演了BBC电视剧《龙的对手》，饰演二战拆弹专家，还出演了《豺狼之日》。1979 年，他在《祖鲁黎明》中饰演哈福德中尉，1980 年在《尼金斯基》中饰演伊戈尔·斯特拉文斯基，1982 年在《艾芬豪》中饰演约翰王子，1983 年，他在《移动》中与佩内洛普·基思演对手戏，1988 年在 BBC 迷你剧《狮子、女巫和衣橱》（1988 年电视连续剧）中饰演阿斯兰，1990 年他出演了短命的情景喜剧， 不是砰的一声。更现代的角色包括《霍恩布洛尔》、《喧嚣》、《福伊尔的战争》、《Midsomer Murders》、《唤醒死者》、《比尔》、《沉默的证人》、《夏洛克·福尔摩斯》和《莫尔斯探长》中的角色。他也是 BBC 情景喜剧《我生命中最糟糕的一周》中的常规角色。他最近一次露面是在霍尔比城饰演查尔斯·伯恩勋爵。

皮卡在根据奥利维亚·曼宁（Olivia Manning）的作品改编的BBC系列剧《战争财富》（Fortunes of War）中饰演一位腐朽的俄罗斯贵族，表演广受好评。他还在 BBC 改编的《纳尼亚传奇》中为阿斯兰配音，并在 1989 年第 4 频道连续剧《行为不端》中与朱迪·丹奇演对手戏。

他也是一位多才多艺的舞台演员。1998年，他因在《艾米的视角》中的表演而获得1997年劳伦斯·奥利弗戏剧奖最佳配角奖提名。

皮卡在雷纳托·卡斯特拉尼（Renato Castellani）编剧和导演的广受好评的《威尔第的一生》中饰演作曲家朱塞佩·威尔第（Giuseppe Verdi）。2005年，他在家庭电影《灰衣修士鲍比历险记》中担任配角。

2009年3月至8月期间，他在肖恩·马蒂亚斯（Sean Mathias）制作的塞缪尔·贝克特（Samuel Beckett）执导的《等待戈多》（Waiting for Godot）中饰演幸运儿，与伊恩·麦凯伦爵士（Estragon）、帕特里克·斯图尔特（Patrick Stewart）（弗拉基米尔）和西蒙·卡洛（Simon Callow）演对手戏。巡演在莫尔文开始，然后前往米尔顿凯恩斯、布莱顿、巴斯、诺维奇、爱丁堡和纽卡斯尔;由于需求，它在皇家剧院的演出，干草市场被延长了。

2010 年 2 月，他还在 BBC 的时代剧《Lark Rise to Candleford》中饰演“Pegleg”。

Pickup was born in Chester, England, the son of Daisy (née Williams) and Eric Pickup, who was a lecturer.[1] Pickup was educated at The King's School, Chester, trained at the Royal Academy of Dramatic Art (RADA) in London, and became an Associate Member of RADA.

His television work began with an episode during the second series of Doctor Who in 1964, for which he was paid £30. Pickup worked with Laurence Olivier at the Royal National Theatre, most notably in Three Sisters and Long Day's Journey Into Night. In 1973, he starred in the BBC drama series The Dragon's Opponent, playing a World War II bomb disposal expert and also appeared in The Day of the Jackal. He played Lt. Harford in Zulu Dawn in 1979, portrayed Igor Stravinsky in Nijinsky in 1980, Prince John in Ivanhoe in 1982, and in 1983 he appeared opposite Penelope Keith in Moving, in 1988 in the BBC miniseries The Lion, the Witch and the Wardrobe (1988 TV Serial) as the voice of Aslan, and in 1990 he starred in the short lived sit-com, Not with a Bang. More modern roles have included parts in Hornblower, Hustle, Foyle's War, Midsomer Murders, Waking the Dead, The Bill, Silent Witness, Sherlock Holmes, and Inspector Morse. He is also a regular character in the BBC sitcom The Worst Week of My Life. His most recent appearance was in Holby City as Lord Charles Byrne.

Pickup gave a highly acclaimed performance as a decayed Russian aristocrat in the BBC series Fortunes of War, based on a work by Olivia Manning. He also provided the voice for Aslan in the BBC's adaptation of the Chronicles of Narnia and starred opposite Judi Dench in the 1989 Channel 4 serial Behaving Badly.

He is also an accomplished stage actor. He was nominated for a 1998 Laurence Olivier Theatre Award for Best Performance in a Supporting Role of 1997 for his performance in Amy's View.

Pickup had the starring role as composer Giuseppe Verdi in the acclaimed The Life of Verdi, written and directed by Renato Castellani. In 2005, he had a supporting role in the family-based film, The Adventures of Greyfriars Bobby.

Between March and August 2009, he starred as Lucky in Sean Mathias' production of Waiting for Godot by Samuel Beckett opposite Sir Ian McKellen (Estragon), Patrick Stewart (Vladimir) and also Simon Callow (Pozzo). The tour opened in Malvern before travelling to Milton Keynes, Brighton, Bath, Norwich, Edinburgh and Newcastle; its run at the Theatre Royal, Haymarket was extended due to demand.

In February 2010 he also appeared as 'Pegleg' in the BBC's period drama Lark Rise to Candleford.

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