Dougal Wilson is a director of commercials and music videos for artists including Coldplay, Massive Attack, Will Young, Goldfrapp, The Streets, Bat for Lashes, Basement Jaxx, Dizzee Rascal and Jarvis Cocker. His many commercials include those for Apple, IKEA, the BBC and Amnesty International. Dougal's adverts for UK department store John Lewis have become a widely talked-about part of British popular culture. His three-minute advert We're the Superhumans, promoting Channel 4's broadcast of the 2016 Summer Paralympics in Rio de Janeiro, garnered the Grand Prix for Film at Cannes Lions in 2017.

In 2007, he co-directed a short film called Rubbish starring Martin Freeman and Anna Friel. In 2010, a short film written by Richard Curtis and directed by Wilson entitled No Pressure was released by the 10:10 campaign in Britain to spread awareness of climate change. He is set to direct Paddington in Peru, the third film in the Paddington franchise.