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Domenica Cinque was an Italian entertainment television news program broadcast every Sunday on Canale 5 and rerun on Mediaset Plus and Mediaset Extra. It was produced in collaboration with Videonews.

Pomeriggio Cinque is an Italian entertainment television news program broadcast every afternoon on the Italian television channel Canale 5, with reruns on Mediaset Plus and Mediaset Extra.

Mattino cinque is an Italian infotainment television program. It airs every morning, from Monday to Friday, on Canale 5 and reruns on Mediaset Plus. It is produced in collaboration with Videonews.

Chi vuol essere miliardario? was an Italian game show based on the original British format of Who Wants to Be a Millionaire?. The show was hosted by Gerry Scotti. The main goal of the game was to win 1,000,000,000 Italian lire by answering 15 multiple-choice questions correctly. There were three lifelines - fifty fifty, phone a friend and ask the audience. Chi vuol essere miliardario? was broadcast from 2000 to 2001. It was shown on the Italian TV station Canale 5. When a contestant got the fifth question correct, he left with at least ₤1,000,000. When a contestant got the tenth question correct, he left with at least ₤32,000,000. There was one winner of the show, Francesca Cinelli. Since 2002 the show is called Chi vuol essere milionario?, after the transition of Italy's currency to Euros.

TG5 is the brand for Italian TV channel of Mediaset network Canale 5's news programmes. They are shown domestically on Canale 5 and Mediaset Plus several times throughout the day. The audience of this newscast, notably in its 08:00 PM edition, has by far the highest audience among commercial TVs in Italy. The show broadcasts from Rome. The present editor-in-chief is Clemente Mimun.

Matrix was an Italian news program and talks show television, broadcast on Canale 5, from 2005 and 2012, and rerun on Mediaset Plus: it was a rival program of RAI flagship news program Porta a Porta.

48 hours is a television series produced in Italy in 2006 by Mediaset. The program was first broadcast during primetime television on 8 March 2006 on Canale 5 where it received negative ratings. It was moved to Italia 1 for the next summer. The drama is now repeated on the pay channel Joi and sometimes late at night on Italy 1.

Verissimo, initially titled Verissimo - Tutti i colori della cronaca is an Italian entertainment television news program covering events and celebrities which debuted on 1996 on Canale 5. It has been produced in collaboration with TG5 until 2006, when the program switched to Videonews.

From September 1996 until June 2006, it was a daily show, initially hosted by the journalist Cristina Parodi and the replaced by Benedetta Corbi and Giuseppe Brindisi and after by Paola Perego. From September 2006, it became a weekly show hosted by Silvia Toffanin and entirely dedicated to gossip and interviews.

Italy, Spain, Germany, Russia, Greece, and Poland are taking part in the Italian reboot of Jeux Sans Frontières filmed at Cinecittà World, Rome. The competitors wear outlandish costumes and do bizarre tasks in funny games.

Three part comedy special.

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Ever since the death of his wife, the famous and once highly-respected general Michael Strogoff has fallen steadily into a state of decrepitude.

Captain De Santis does not only carry out peace-keeping operations; he is also looking for the truth behind his father's disappearance in the zone. When he starts untangling a scandalous plot of corruption and death, where pharmaceutical companies, secret services and terrorists are involved, he becomes a target.