A Canadian reality television show in which a group of contestants, known as "house guests", are sequestered in the Big Brother House, under the surveillance of cameras and microphones, for the chance to win a grand prize of $100,000 by being the last remaining house guest. Each week, the house guests vote to evict one of their own until two house guests remain on finale night. The winner is decided by the last seven evicted house guests, known as the Big Brother Jury.

Til Debt Do Us Part is a Canadian television series produced by Frantic Films for Slice in Canada, Zone Reality in the United Kingdom and AmericanLife TV Network and CNBC in the USA. It is hosted by Gail Vaz-Oxlade, who each week visits a couple who are in debt and having relationship troubles. The participants are given weekly challenges, some of which are to help bring the finances and debt under control, with the others meant to help the couple's relationship. At the end of one month, Vaz-Oxlade gives the couple a cheque for an amount up to $5,000, depending on how well they did during the challenges.

Intervention Canada is a Canadian reality TV series based on the A&E show Intervention, and airs on Slice, Sundays at 8 pm. It is now in its second season.

Intervention Canada profiles people whose dependence on drugs and alcohol or other compulsive behavior has brought them to a point of personal crisis or estranged them from their friends and loved ones. Each episode ends with a surprise intervention that is staged by the family and friends of the addict, conducted by addiction specialists.

On February 9, 2012 Slice had announced on their Facebook that the show is cancelled.

Project Runway Canada is a Gemini Award-winning Canadian television adaptation of the American reality television series Project Runway, which debuted on the Slice network on October 8, 2007. The second season aired on Global. The series' host is fashion model Iman, while Canadian designer Brian Bailey acts as the contestants' mentor. The series was canceled over one year after the second season finale.

An unprecedented behind-the-scenes access to two of Canada’s busiest hospital emergency rooms.

Dramatic and emotionally-charged, the verité-style series follows the real-life experiences of eleven expecting women as they face the complexities of pregnancy, the intensity of giving birth and the realities of bringing a new life into the world.

Birth Stories is a Canadian documentary television series that aired from 2000 to 2004 on Slice. It is produced by Cineflix, Slice and Sky Living.

Follow some of toronto's most privileged, powerful and glamorous women as they navigate the elite social scene of Canada’s largest city.

In every high-style-meets-high-stakes episode, four competitors face off in dramatically themed challenges with one designer eliminated each round.

The List is a Canadian reality television series, which debuted on November 13, 2007 on Slice. Hosted by Liza Fromer, the show will give participants the opportunity to live out a dream or goal.

This show is another aution hunter show, except this takes place in Ontario. Lost luggage and lost items in transit are auctioned. Get some friends together and turn each episode into a drinking game as the four regular cast members make dry attempts at humor.

Alan Thicke, one of Hollywood’s most famous TV dads, stars in the role of his life in Unusually Thicke, an original reality sitcom—but not even seven seasons as Dr. Jason Seaver on Growing Pains could prepare him to be the patriarch of his own real-life modern family. Between his feisty younger wife, Tanya, his opinionated teenage son, Carter, and his iconic career, Alan has his hands full in a unique series that follows the family’s daily drama and humor.

Superstar Hair Challenge is a reality TV show on Slice Network hosted by Karen Bertelsen. Contestants must complete hair design related challenges, and a person is eliminated each week.

Princess is a Canadian television series hosted by Gail Vaz-Oxlade that premiered in 2010. The program is similar in format to her earlier endeavor, Til Debt Do Us Part; however, rather than helping couples in financial trouble, Vaz-Oxlade assists women who are considered self-indulgent and spoiled. Participants are given weekly challenges, some of which are to help bring the finances and debt under control, while others are meant to help correct the participant's attitude and make amends to their friends and relatives. At the end of six weeks, Vaz-Oxlade gives the participant a cheque for an amount up to $5,000, based upon Vaz-Oxlade's assessment of the participant's success in each of the challenges.

In the United States, the show airs on Saturday nights on cable news channel CNBC.

Dogs with Jobs is an in-depth documentary series that sniffs out the best stories about working dogs. Combining on-the-job footage with great storytelling, the series showcases a wide variety of breeds, and jobs, from all over the world. Each half-hour episode features three hard-working rescue dogs, guide dogs, scent detectives or entertainers and delves into the science behind canine behaviour to show us how and why they do what they do.

Bulging Brides is a Canadian television series produced by Slice, and shown on Slice and Discovery Health Channel in Canada and the WE: Women's Entertainment network in the US.

Bulging Brides is a television series that focuses on a bride’s desperate struggle to drop unwanted inches so that she can look picture perfect on her wedding day. The series is co-hosted by The Last 10 Pounds Boot Camp's “Dream Team”: personal trainer Tommy Europe and nutrition specialist Nadeen Boman.

Each half-hour episode features the story of one bride-to-be in the high-anxiety period less than two months before the big day. The bride has her wedding dress, but it doesn’t fit. Racked by tension from the bridal arrangements and petrified by the thought of not feeling her best on her big day, the bride-to-be has turned to the Dream Team as a last resort to lose her excess weight and fit in her gown.

Sex, Toys, & Chocolate is a talk show produced by Alliance Atlantis on cable and satellite in Canada. Premiering on March 5, 2004, new episodes appeared on Life Network and older ones ran on Discovery Health network. It was hosted by Robin Milhausen and Michael Cho. Each show opens with interspersed scenes of Milhausen and Cho discussing some sex-related topic with three women and three men respectively. The men and women are then brought together for a group discussion, followed by role-playing or trivia games at the end. Field reporter Roy Roman interviews people on the streets of Miami about the same topic, which typically include oral sex, masturbation, fetishes, orgasm, pornography, and the like. The show includes explicit language and discussion not seen on American television and is distinguished from other sex-related television series in that it is primarily designed to convey the opinions and experiences of average people and not to convey expert advice.

The Last 10 Pounds Bootcamp is a Canadian television show on the Slice network that puts participants through an intense fitness and nutrition routine designed to help them reach a target weight in four weeks. The participants are usually motivated to lose weight by a wedding or some other important upcoming event in their lives. The show stars Tom Europe, a former CFL star turned celebrity trainer, who plays the role of the drill instructor at the bootcamp. Europe is often accompanied by Nadeen Boman, who helps the participants on the show learn about nutrition.

Chop Shop is a Canadian docusoap television series created, directed and produced by Ziad Touma that premiered on February 4, 2009, on the Slice Network. The show follows the stylists at a rock and roll hair salon in Vancouver, British Columbia. The series was produced by Paperny Films.

Wedding SOS is a Canadian television series shown on the Slice Network in Canada, the Fine Living network in the US, Sky Livingit in the UK and The Style Network in Australia.

The premise of each episode has a couple in over their heads planning a wedding, and brings in wedding expert Jane Dayus-Hinch to assist the couple to salvage the wedding. Dayus-Hinch is known as a fairy God-mother who grants the couple three wishes. She is also the ex-wife of former Judas Priest drummer John Hinch.