In 1921, Titanus released a three-part serial based on a popular Italian novel from the turn of the 20th century: Nobody’s Children by Ruggero Rindi. The tale of lovers thwarted by class differences, of illegitimate children and parental recognition denied was a major success for producer Gustavo Lombardo and leading lady Leda Gys.

I figli di nessuno è un film muto del 1921, diretto, interpretato e sceneggiato da Ubaldo Maria Del Colle, tratto dall'omonimo dramma teatrale di Ruggero Rindi e Vittorio Salvoni.