There is a war going on between Heaven and Hell. Earth is the battlefield. Human souls are the prize. On the front lines, where good and evil collide, is a soldier in search of his past and his future. Spawn, formerly known as Al Simmons, is a CIA hitman whose death causes him to seal a deal with the devil so that he can return to his wife Wanda. Instead, the devil transforms him into 'hell-spawn,' a dark warrior who battles the forces of evil on Earth--and in himself--to uncover the truth about his identity and fulfill his destiny.

Al Simmons, agent du service action, employé par une organisation gouvernementale secrète, est trahi par son supérieur, Jason Wynn, qui le fait perir dans l'explosion d'une usine d'armes biochimiques. Simmons se retrouve alors devant Malebolgia, seigneur des ténèbres. Il signe avec lui un pacte lui permettant de revoir sa femme. Il devra mener les armées du mal dans leur ultime combat. Simmons devient alors un guerrier infernal à la force et aux pouvoirs illimités : Spawn !

Al Simmons, un superagente del gobierno, es asesinado por su jefe, el malvado Jason Wynn, con la ayuda de su terrible colaborador Clown. Deseando volver a ver a su amada Wanda, y cegado por la venganza, Simmons decide hacer un pacto con el diablo.