两个朋友，杰克·弗罗斯特和奈特，在阿富汗战争中幸存…但战争的激烈程度以不可逆转的方式改变了两人。杰克·弗罗斯特成为一个绘画大师和骗子。Nat变成了吸血鬼。这两个以前的朋友现在互相对立，因为这些生活方式自然会引起冲突。一个经典的行骗高手必须杀死他现在的吸血鬼-前-最好的朋友的故事。另外，Gary Busey作为一个艺术收藏家和咨询分销商来到这里。每次持续几分钟。

San Diego, present day: The murders are starting again. A girl has been found with two holes in her neck and her body totally drained of blood. Lt Dan Richardson [Shane Pliskin] knows what it is but doesn't believe it, so he calls in blind art-dealer Micah [Gary Busey]. Micah confirms the lieutenant's suspicion that a vampire is at work and reminds him of the previous lesson learned by Jack Frost, who was forced to kill his best friend Nat McKenzie when Nat became a vampire.

Deux mercenaires, Jack Frost et Nat McKenzie, sont envoyés en mission. Durant leur périple, Nat est mordu par une créature maléfique et, de retour aux Etats-Unis, commence à se métamorphoser en un monstre de plus en plus puissant...