何芝芝自小就容易得到男性倾心，每当男性与其结婚不久，立刻就升官发财，但是没过多久却都死于非命。

为妇女请命的苏大忠，与芝芝婚后成为香港知名运动人士，却在一次意外中变成水泥立像；搞笑艺人小高在夜总会不得志，与芝芝婚后成为最炙手可热的脱口秀表演者，却在舞台上被飞来的酒瓶意外砸中头部身亡；卧底警员小卢贪生怕死，与芝芝婚后成为苏格兰训练场最佳勇探，却在一次逮捕抢匪的行动中被大型集装箱压死。

王杰遇到芝芝便一见倾心，两人交往不久，就让王杰萌生结婚念头，但是芝芝怕王杰跟以往夫婿有相同遭遇，于是迟迟不肯答应。于是王杰联合所有芝芝友人，打算来个破除迷信的计中计。

The gorgeous Cherie Chung is a cursed bride in the hilarious romantic comedy 18 Times! Gigi (Cherie Chung) is a young woman with no shortage of potential husbands to choose from. The big problem: every single one of her husbands dies after becoming wealthy! As a result, Gigi is obscenely rich, but she can't seem to find a "Mr. Right" that won't die! Numbers one through seventeen all get shuffled off the mortal coil, making Gigi promise to never love again. But when charming Jack Wong (Kenny Bee) shows up, will Gigi risk love for the eighteenth time? Director Joe Cheung creates laughs and hijinks aplenty, and a full cast of Hong Kong cinema stars - including Teresa Carpio, Sing Fui On, and John Sham, Eric Tsang, and Lowell Lo as three of Gigi's doomed husbands - turn in hilarious, self-effacing performances. Cherie Chung and Kenny Bee risk his death for their love in 18 Times!