I think everyone has a wish list for what the fifth Indy film, if it ever happens, focuses on. For me, I'd like to see Indiana Jones and the Fountain of Youth. Not because I'd like to see a de-aged Harrison Ford, because I wouldn't, but because it would allow the filmmakers to acknowledge the age of its hero and allow him to address his own mortality. I think the Fountain is a fantastic macguffin, something that men have sought for literally thousands of years, and would make a great excuse to go globe-trotting. (I know they kind of poked at this with the Holy Grail, but it ended up just being some "super healing water" and little else.)

I don't think anyone believes there would ever be an Indiana Jones 6, so my hope is that Spielberg (without Lucas's involvement, but hopefully Darabont's) can restore legitimacy to the franchise one last time. I want practical effects! I want a REAL Marion Ravenwood one last time! I don't want ANY Shia! I'd love to see Indiana pass his hat to the next generation! And I'd like to see charming Harrison Ford one last time.

@AlienFanatic said:

I want practical effects!

Kingdom of the Crystal Skull had heaps of practicals as links related shows:

https://postimg.org/image/rnl3w0ubt/

https://postimg.org/image/aaph7zg47/

I love how they actually made the brick stairs retract