Marcy Meyers is down on her luck. Faced with piling bills, the remnants of a failed marriage, and now an imminent home foreclosure, she has nowhere to turn but to the hope of a miracle. That miracle she finds in Shoot the Moon, a national game show that promises a one in a lifetime chance to win it all. But Marcy's faith in the show comes with a price. As her relationship with her daughter Alice is put to the test, the clock ticks towards a seemingly inescapable fate. Shoot the Moon tells the story of miracles and the extraordinary place they are found.

Marcy Meyers est au bout du rouleau. Les factures s’accumulent, son mariage est un échec et sa maison risque d’être saisie. Elle place tous ses espoirs dans un jeu télévisé qui lui permettrait de « décrocher la lune »…