Five miles below the Earth's surface, a group of scientists is working in self-imposed isolation, perfecting a series of DNA experiments that could literally change the world. But when one of those experiments goes awry, it unleashes a nearly immortal organism--one capable of instant regeneration, and with an insatiable appetite for living flesh. Soon, nothing can contain the creature, and with the lab's life support systems quickly shutting down, the scientists grimly prepare for their final battle... A small group of scientists are working in self-imposed isolation below the Earth's surface. They are all working to create DNA which could change the world, but one of the scientists have been given an secret assignment, and when the assignment goes wrong, all hell breaks lose. The new creation is now aboard the ship and will destroy anyone who gets in its way, as it moves towards the surface.

Sechs Forscher lassen sich in einem Labor fünf Meilen unter der Erdoberfläche einschließen. Einer der Männer arbeitet auf eigene Faust und injiziert einer Ratte einen besonders fiesen Virus. Das Experiment misslingt. Das Versuchstier entwischt, bringt einen der Wissenschaftler um und nistet sich in dessen Körper ein. So will es einen Wissenschaftler nach dem anderen zur Strecke bringen...