根据南Q太的同名少女漫画改编，普通上班族夕子爱上了一同打工的男子裕，两人开始交往，裕却一直说自己在冲绳有一个叫绿子的女朋友，裕还有很多关系暧昧的异性朋友。围绕着他们，还有另外一对分别暗恋着夕子和裕的男孩和女孩。身体的出轨与内心的执著相互纠缠，每个人都死守着自己内心最后一块角落 ……

Naive office girl Yuko supports her blithe big city lifestyle with a part-time job at a neighborhood cafe. Attracted to her manager there, the shallow but charming Yutaka, she willingly succumbs to his lascivious advances only to discover afterward that he already has a girlfriend by the name of Midori. Even so, Yuko's feelings for Yutaka continue to grow regardless of his aloofness. Before long she finds herself reluctantly cajoled into working as a hostess in a small karaoke bar. Fatalistically accepting his dalliances with flames old and new, she perseveres not so much in hope of a more substantial relationship, but rather out of fear of losing him. There are other men out there waiting for her -- kinder, more considerate and eagerly available. But for Yuko, there is only the non-committal, yet torridly magnetic Yutaka. Why him? Not even Yuko seems to know the answer.

お茶汲みOL・ゆうこはいい加滅なカフェ店員。ユタカのことが好き。初めてユタカと寝た日、ゆうこはユタカにみどりという彼女がいることを知った。ユタカに嫌われたくない一心で何も言えないゆうこは、ユタカにすすめられるがまま、スナックでホステスのバイトを始める。お互いの電話番号も知らないまま、二人の畷昧な関係は続いて行くが…。 軽くてだらしなくてデリカシーのない男。でも好きになってしまう、彼の磁力にとらわれてしまう。他に優しい男ならいくらでもいる。でも彼じゃないとだめなんだ、なんでだろう。 リアルで切ない恋愛模様を描かせたら右に出るものはいない南Q太の傑作コミック『さよならみどりちゃん』、待望の映画化である。