Amelie no es una chica como las demás. Ha visto a su pez de colores deslizarse hacia las alcantarillas municipales, a su madre morir en la plaza de Nôtre-Dame y a su padre dedicar todo su afecto a un gnomo de jardín. De repente, a los veintidós años, descubre su objetivo en la vida: arreglar la vida de los demás. A partir de entonces, inventa toda clase de estrategias para intervenir en los asuntos de los demás: su portera, que se pasa los días bebiendo vino de Oporto; Georgette, una estanquera hipocondríaca, o "el hombre de cristal", un vecino que sólo ve el mundo a través de la reproducción de un cuadro de Renoir.
Kassie Larson desea tener un hijo por inseminación artificial. En medio de una fiesta y con unas copas encima, Wally reemplaza el semen del donante por el suyo. Al despertar, él no recuerda nada de lo sucedido, por lo que ninguno de los 2 saben tienen un hijo juntos.
El marido de Hannah tiene un romance con una hermana, y su ex-marido termina casándose con la otra hermana.
Calvin (Asa Butterfield) es un hipocondríaco que trabaja como encargado de equipaje de un aeropuerto. Cuando conoce a Skye (Maisie Williams), una adolescente británica que padece una enfermedad terminal, su vida cambia por completo. Su nueva e impulsiva amiga le contrata para que le ayude a cumplir su lista de tareas pendientes antes de morir, una misión que le obligará a luchar contra sus peores miedos.
George Kimball es un hombre hipocondriaco que, convencido de que una enfermedad acabará pronto con su vida, decide arreglar sus asuntos antes de que llegue el día fatal. Lo único que le preocupa es su encantadora esposa, de modo que, con la ayuda de su mejor amigo, empieza a buscarle un marido.
Quinn, a neurotic man, is diagnosed with a harmless eye condition and soon after his life spirals out of control. He second-guesses his plans to propose to his longtime girlfriend, Devon, after his beautiful coworker, Kelsey, confesses that she has a crush on him. After a conversation with his best friend, Jameson, he clumsily tries to explain his doubts to Devon, but his possible proposal turns into a break-up. When Devon flees to Paris, he follows her in a last-ditch effort to win back "the one."
The sexual relationship between a successful woman and her brother, an introvert, hypochondriacal youth, who is also a pornophile.
Romain Faubert is a 39 year old, single, medical photographer... and a raging hypochondriac. His doctor and only friend Dr. Dimitri Zvenka thinks he knows the cure for Romain: dating! But with the arrival of freedom fighter Anton Miroslav, everyone might get more then they bargained for...
Odile is a business executive looking for a new, bigger apartment. Her younger sister Camille has just completed her doctoral thesis in history and is a Paris tour guide. Simon is a regular on Camille's tours because he's attracted to her. Camille has fallen for Marc, and they begin an affair. Nicolas is also looking for an apartment, since he hopes to eventually have his family join him in Paris.
A gang of thieves plan to make their fortune by stealing a shipment of contraceptive pills from Finisham maternity hospital. They assume disguises and infiltrate the hospital, but everything doesn't go according to plan. The hypochondriac consultant Sir Bernard Cutting, Matron and the doctors and nurses at Finisham have a habit of getting in the way.
A small town doctor mistakenly ingests an experimental drug made from the blood of vampire bats which transforms the kindly medic into a bloodthirsty monster.
Young boxer Michel Maudet is sacked by his manager after a series of match defeats and is forced to look for a new job. He is engaged as secretary to a millionaire named Ferchaux who is in a hurry to flee the country when he discovers he has been implicated in a high-profile fraud.
Jim is afraid of everything. In order to face his fears, Jim will bring everything he is afraid of into his house. It doesn't quite work out as expected..
Tucked away in his castle, a hypochondriac inventor plays generous host to a revolving cast of wacky guests. But to pay off his mounting debts, he must sell either a powerful businessman or a rich gypsy on his latest creation: a laser skywriter.
Dr. Steven Bishop is taken to the hideout of Frank Dillon and his gang to treat the wounded Joe Madison. Joe's nurse sister Nora Madison is also taken. Dillon tells Bishop that if Joe dies, he will be killed, but Bishop knows he will be either way. Joe dies, but Nora and Steve conceal it from Dillon and send a plea for help in a prescription that Bishop writes in Latin.
Rich 'Old Man' Bill Morton is a hypochondriac. After bringing new sugar pills to Bill Morton's house, his physician, Doctor Malcolm Scott suggested to Bill Morton's wife that adopting a child might help cure Mister Morton of his delusions. After overhearing their conversation, Bill Morton quickly invited the "Our Gang" members, (as they were at the front come to the door, offering to work and pay for a broken window pane, that had just occurred) to a lunch, in order to sour his wife's thoughts of adopting any children. Then, the unexpected occurs as Alfalfa's two twin little brothers, Tisket and Tasket got to Bill Morton's medications' table, they ate up a majority of them, leading Bill Morton to call his physician, Malcolm Scott back to his house, immediately! When, Doctor Malcolm Scott return to Bill Morton's house, he laughs at what he hears and then tells Bill Morton they are worthless sugar pills, teaching a lesson to Bill Morton he is not sick at all.
When his best friend dies of a heart attack, Ray Macklin becomes a man obsessed with his own mortality. Convinced that all his aches and pains are an indication of his imminent death, Ray's life turns into a slapstick farce of health-crazed anxiety and hypochondria.
A hypochondriac is afraid he will die before he gets an inheritance that will "cure" him.
Fascinated by his friend's success abroad, an out-of-work barber Šurda tries his luck in Germany. Incapable to accept any job that would suit him, he returns to his homeland in disappointment. Based on a popular TV serial "Hot Wind" ("Vruć vetar").
Donald's got the day off, and all he can think of is golf until it rains as soon as he sets foot outside. He takes it out on his nephews. When he's sitting around moping, they take revenge by playing off his hypochondria.