Vignettes weaving together the stories of six individuals in the old West at the end of the Civil War. Following the tales of a sharp-shooting songster, a wannabe bank robber, two weary traveling performers, a lone gold prospector, a woman traveling the West to an uncertain future, and a motley crew of strangers undertaking a carriage ride.
Bounty hunters seek shelter from a raging blizzard and get caught up in a plot of betrayal and deception.
A small-town sheriff in the American West enlists the help of a disabled man, a drunk, and a young gunfighter in his efforts to hold in jail the brother of the local bad guy.
A group of people traveling on a stagecoach find their journey complicated by the threat of Geronimo, and learn something about each other in the process.
Questions arise when Senator Stoddard attends the funeral of a local man named Tom Doniphon in a small Western town. Flashing back, we learn Doniphon saved Stoddard, then a lawyer, when he was roughed up by a crew of outlaws terrorizing the town, led by Liberty Valance. As the territory's safety hung in the balance, Doniphon and Stoddard, two of the only people standing up to him, proved to be very important, but different, foes to Valance.
John Russell, disdained by his "respectable" fellow stagecoach passengers because he was raised by Indians, becomes their only hope for survival when they are set upon by outlaws.
Jesse W. Haywood (Don Knotts) graduates from dental school in Philadelphia in 1870 and goes west to become a frontier dentist. Penelope "Bad Penny" Cushing (Barbara Rhoades) is offered a pardon if she will track down a ring of gun smugglers. She tricks Haywood into a sham marriage as a disguise. Haywood inadvertently becomes the legendary "Doc the Haywood" after he guns down "Arnold the Kid".
A group of unlikely travelling companions find themselves on the same stagecoach to Cheyenne. They include a drunken doctor, a bar girl who's been thrown out of town, a professional gambler, a travelling liquor salesman, a banker who has decided to embezzle money, a gun-slinger out for revenge and a young woman going to join her army captain husband. All have secrets but when they are set upon by an Indian war party and then a family of outlaws, they find they must all work together if they are to stay alive.
After her stagecoach is ambushed, a woman is tasked with holding a dangerous outlaw captive and must survive the day when the bandit’s gang tries to free him.
An independent former ranch foreman and an heiress are kidnapped by a trio of ruthless outlaws.
Story follows a stagecoach ride through Old West Apache territory. On board are a cavalry man's pregnant wife, a prostitute with a broken heart, a Marshal taking in his prisoner Johnny Ringo, a crooked gambler, and the infamous Doc Holliday
At a desolate relay station in the west, a stagecoach attendant and a stranded woman traveller are held captive by a band of escaped convicts.
A peace-loving man named Ben Kane takes a job as deputy marshal of Lords, in the old West. Kane is no lawman, but he accepts the badge because he has an old score to settle with the town's chief trouble-maker. Once on the job, Kane must also deal with a young sharpshooter named Billy Young and a sharp and sassy saloon dancer, Lily.
Two Virginians are heading for a new life in Texas when they witness a stagecoach being held up. They decide to rob the robbers and make off with the loot. To escape a posse, they split up and don't see each other again for a long time. When they do meet up again, they find themselves on different sides of the law. This leads to the increasing estrangement of the two men, who once thought of themselves as brothers.
When the owner of a stagecoach station is killed, a gunman takes his place.
Union officer Kerry Bradford escapes from a Confederate prison and races to intercept $5 million in gold destined for Confederate coffers. A Confederate sympathizer and a Mexican bandit, each with their own stake in the loot, stand in his way.
Lambert has the stagecoach wrecked killing the Commissioner so his phony replacement can alter Coonskin's land survey. When Red Ryder exposes the survey hoax, Lambert has his stooge Sheriff put Red in jail.
An Arizona frontiersman steals an Indian agent's girlfriend, followed by trouble.
During the French Revolution, a surprising company shares a coach, trying to catch up something - the time itself, perhaps.
Case Britton, gunslinger and wanted man, comes to town to meet his bride-to-be, stop a stagecoach robbery, and get even with the man who killed his brother.