John Constantine wakes up in the eerie House of Mystery with no recollection of how he got there. Fortunately, Zatanna and his friends are all there. Unfortunately, they have a bad habit of turning into demons and ripping him to shreds, over and over again!

A decade after a tragic mistake, family man Chas Chandler and occult detective John Constantine set out to cure his daughter Trish from a mysterious supernatural coma.