Tobacco, climate change, pesticides,... Never has scientific knowledge seemed so vast, detailed and shared. And yet it appears to be increasingly challenged. It is no longer surprising to see private corporations put strategies in place to confuse the public debate and paralyze political decision-making. Overwhelmed by excess of information, how can we, as citizens, sort out fact from fiction? One by one, this film dismantles the workings of this clever manoeuvre that aims to turn science against itself. Thanks to declassified archives, graphic animations and testimonies from experts, lobbyists and politicians, this investigation plunges us into the science of doubt. Along with a team of experts (philosophers, economists, cognitive scientists, political men, or even agnotologists), we explore concrete examples of doubt making and try to understand the whole process and the issues behind it.

Composer Gary Stuart (Ray Milland) and his wife, Connie (Jane Wyman), have an argument over her alleged affair with Courtney Craig (Tom Helmore). The Stuarts agree to get divorced, and each tries to move on to a new love: Gary with socialite Deborah Randolph (Karin Booth) and Connie with businessman Frank McGraw (Aldo Ray). However, they start to realize that they still have strong feelings for each other. The Stuarts must make a decision before their divorce is final.

A young academic decides to accept guardianship of the daughter of a late friend. Expecting her to be a young child, the household is shocked to find out she is in fact a young woman. The two marry but more miscommunications cause troubles in their relationship.

A production company holds a public competition for film ideas. The winning letter tells of a young woman's lost love in the 1840's. It is, in fact, the true story of a now elderly woman's life.