Jennifer Walters navigates the complicated life of a single, 30-something attorney who also happens to be a green 6-foot-7-inch superpowered hulk.

Deciding to turn over a new leaf, a group of friends who also happen to be vampires and werewolves move into a house together, only to find that it is haunted by ghosts of people who have been killed under mysterious circumstances. As they deal with the challenges of being supernatural creatures, their desire to be human bonds them.

Lucy, deklica z izjemnimi psihičnimi sposobnostmi, se pridruži dvema nadarjenima najstnikoma, Anthonyju in Georgeu, v agenciji za lov na duhove poimenovana Lockwood & Co., da bi se borili proti smrtonosnim duhovom, ki pestijo London. Po svojih najboljših močeh se trudijo rešiti dan brez nadzora odraslih in tvegajo še tisto malo, kar imajo, da razkrijejo diabolično zaroto.