少年戰鬥著 —「為了尋求正確的死亡」辛酸、後悔、恥辱人類產生的負面情感，化為詛咒，潛入日常生活詛咒是蔓延於世界的禍源，最糟糕的情況下，會讓人類踏入死亡並且，詛咒只能以詛咒祓除擁有驚人身體能力的少年·虎杖悠仁原本過著普通的高中生活有一天，為了拯救被「詛咒」襲擊的同伴，他吃下了特級咒物「兩面宿儺之指」，讓詛咒寄宿於自己的靈魂之中與詛咒「兩面宿儺」共有肉體的虎杖，在最強咒術師五條悟的指引下，進入對詛咒專門機關「東京都立咒術高等專門學校」……。為了祓除詛咒而成為詛咒的少年，無法回頭的壯闊故事開始了。

以腹黑毒舌的暗黑精靈「卡菈」與難以煽動的鎧甲男「艾爾文」為主軸，描述兩人間充滿各式吐槽的冒險喜劇。

Dome, a barista at a café on the verge of closure, receives an unexpected job offer. The offer comes from a café regular, Khatha, who orders coffee he never drinks. The job is at an odd museum open only after sunset. With few choices, Dome accepts Khatha's offer.

On his first day, an employee tells him the museum is haunted. Forbidden by the overseer from entering Zone 16, Dome is tempted inside. Khatha attempts to contain the damage, but Dome has unintentionally awakened things and nearly everything inside manages to slip out. Dome takes responsibility and, with Khatha, attempts to hunt down what went missing in order to return them to where they belong.