Vodeća komičarka današnjice Melissa McCarthy u filmu Špijunka glumi Susan Cooper, skromnu CIA-inu uredsku analitičarku koja je junak iz sjene niza najopasnijih misija svoje agencije. Kada njezin partner (Jude Law) završi iza rešetaka, a drugi vrhunski agent (Jason Statham) biva otkriven, Susan će postati posljednja nada tajne operacije koja mora spriječiti najpoznatijeg svjetskog trgovca oružjem da ne izazove globalnu katastrofu.

Physical therapist Leslie Wright lands the dream job of working with basketball superstar Scott McKnight, helping him recover from a career-threatening injury. All goes well and soon Leslie finds herself falling in love with him. Just as their friendship deepens, however, Scott focuses his attention back on his tenuous relationship with his ex-fiancé Morgan, Leslie's gorgeous godsister, who would love to be the basketball player's trophy wife.

A successful veterinarian and radio show host with low self-esteem asks her model friend to impersonate her when a handsome man wants to see her.