Głównym bohaterem jest Cootie, czterometrowy czarny nastolatek z Oakland w Kalifornii. Chłopak dorastał w ukryciu. Wkrótce po raz pierwszy doświadcza piękna i zawiłości świata. Nawiązuje przyjaźnie, znajduje miłość, radzi sobie w dziwnych sytuacjach i spotyka swojego idola - Bohatera.
Yoshihito, a 23-year-old man who has no job or girlfriend. In order to make ends meet he rents out one of the rooms in his house. While he's showing Lily, his first tenant, around the house, she's suddenly attacked by a vampire named Vivian, and Yoshihito notices that Lily is actually a werewolf. As Yoshihito and Lily start living in the same house, Yoshihito is scouted for an organization that maintains order of the parallel universes, and strange creatures one after another become tenants in his house.
Daisū is a a manga creator who grew up in an orphanage, and whose works do not sell very well. Daisū lives each lonely day in boredom, but one day he meets a young man named Myō who has cat ears, and his everyday life completely changes. Myō gets in trouble every day, but for the first time in his life, Daisū’s heart experiences "warmth."