本劇故事大約在《星空奇遇記》事件發生的前十年開始，第一季將看到克林崗家族在與星際聯邦的戰爭後團結起來，這場戰爭嚴重涉及聯邦星艦發現號（NCC-1031）的船員。第二季戰爭結束後，發現號調查了七個神秘信號和一個被稱為「紅天使」的奇異人物。 第三季則是發現號前往32世紀，即他們的未來900多年，為這場衝突畫下句點。第四季描述在《星空奇遇記》事件發生的900多年後，發現號的船員們面臨着一種無形的異常。

New CE 2012. the mysterious organization Vagras aims to threaten the city by stealing the Enetron which is a new power source supporting people’s life. It's up to the Go-Busters to protect the city alongside their partners, the Buddyroids.

A future war has raged for decades between the few human survivors and an endless army of machines. 1997: the AI known as Skynet gained self-awareness and began its war against humanity. Caught between the future and this past is a soldier sent back in time to change the fate of humanity.