Heroin addict Mark Renton stumbles through bad ideas and sobriety attempts with his unreliable friends -- Sick Boy, Begbie, Spud and Tommy. He also has an underage girlfriend, Diane, along for the ride. After cleaning up and moving from Edinburgh to London, Mark finds he can't escape the life he left behind when Begbie shows up at his front door on the lam, and a scheming Sick Boy follows.

A poet falls in love with an art student, who gravitates to his bohemian lifestyle — and his love of heroin. Hooked as much on one another as they are on the drug, their relationship alternates between states of oblivion, self-destruction, and despair.

A junkie must face his true self to kick his drug addiction.

"Popeye" Doyle travels to Marseilles to find Alain Charnier, the drug smuggler that eluded him in New York.

Undercover cop Jim Raynor (Jason Patric) is a seasoned veteran. His partner, Kristen Cates (Jennifer Jason Leigh), is lacking in experience, but he thinks she's tough enough to work his next case with him: a deep cover assignment to bring down the notoriously hard-to-capture drug lord Gaines (Gregg Allman). While their relationship turns romantic during the assignment, they also turn into junkies, and will have to battle their own addictions if they want to bring down Gaines once and for all.

An alcoholic drifter must battle withdrawal and psychotic rednecks after he becomes the target of a deranged sporting event.

Leo Regan follows his friend, photographer Lanre Fehintola, as he tries to go cold turkey (detox) from heroin in his council flat and without medication.

Pluto and the cat, goaded by a TV commercial for turkey, raid the fridge and find a turkey inside. The cat gets there first and re-heats the turkey, first on the furnace duct, and then, trying to hide from Pluto, inside the tube-type TV - but he over-does it a bit.

A junkie couple board themselves in their apartment while they try to kick their heroin habit.

In this chilling documentary about the power of addiction, three friends take their fourth longtime pal Bryant "HairKutt" Johnson to a remote cabin in the Tennessee woods, hoping to force him to kick his heroin habit. The group must cut short their trip when HairKutt's body begins to fail without the drug, and after rushing him to a hospital, the friends are dismayed to find that he quickly returns to his old ways.