Nozomi Yumehara, a regular student, finds a magical book called the Dream Collet in the library and meets Coco and Nuts, two creatures from the Palmier Kingdom. They plead with Nozomi to restore their world, which has been destroyed by an organization called the Nightmares, by completing the Dream Collet and finding the 55 Pinkies to make any wish come true. Meanwhile, the Nightmares are moving into the real world. Once Nozomi agrees to help, Coco and Nuts transform her into the magical girl Cure Dream and turn four fellow students into her Pretty Cure team.

Tsubomi Hanasaki is a girl in the second grade of middle school who likes flowers and plants. One day she experiences a weird dream. In that dream, a large blooming tree appears. Suddenly it is losing all of its flowers and a fairy appears. A few days later after Tsubomi has transferred to Meidou Gakuen, suddenly the fairy from the dream appears before her and pleads to Tsubomi to become the legendary warrior Precure and protect the Heart Tree. However, Tsubomi declines as she doesn't think that she would be able to do that. However, a mysterious enemy suddenly strikes and steals the heartflower of Erika Kurumi, Tsubomi's new classmate. Now she doesn't have a choice. To retrieve Erika's heartflower she has to transform into Precure and fight. Working up the courage Tsubomi turns into Cure Blossom and a new chapter of Pretty Cure begins!

Sade levittää virusta ja hävittää valtaosan Pohjoismaiden väestöstä. Kuusi vuotta myöhemmin kaksi sisarusta etsii nuorten selviytyjien kanssa turvapaikkaa – ja selitystä.

One of the anime projects to commemorate the 20th anniversary of the Precure franchise, this sequel will show Nozomi Yumehara and other characters from Yes! Precure 5 GoGo! and Precure Splash Star as grown-ups.