在工業年代的黃金時期，有個心狠手辣的壓迫者企圖發展一套新研發的武器，配合殘忍的計畫，想拿下整個世界，供他一個人支配。而對抗這種野心作為的責任就落在菁英濟濟的「天降奇兵」隊伍肩上。 史恩康納萊飾演全球最頂尖的冒險家艾倫郭德曼，由他領軍的是一個前所未見，集合眾優秀成員的團隊，原片名「league」指的就是由一群「不凡的紳士」組成的「天降奇兵」。 郭德曼的不凡團隊有尼莫艦長（《雨季的婚禮》奈賽汀蕭飾演）、女吸血鬼米娜哈克（澳洲名模佩塔威爾森飾演）、化身博士（《偷拐搶騙》傑森佛萊明飾演）、隱形神偷羅尼史金納（《刀鋒戰士2》湯尼克倫飾演）、不死美少年德雷安葛雷（《魔咒女王》史都華湯森飾演）、偵探湯姆索耶（《》失戀大聯盟西恩魏斯特飾演）等。而這群人則是由一個叫M的神秘角色（理查羅森堡飾演）所招募而來的。 《天降奇兵》的成員每個都是頑固的個人主義者，被放逐以致於漂泊天涯、同樣有著斑斑可考的輝煌歷史、與生俱來的特殊天賦，是幸運卻也是詛咒。現在，被賦予拯救文明世界的他們必須學習如何信任彼此，學習團隊的分工合作。他們既來不及作足夠的事前準備，也沒有多餘時間可供揮霍，即將被尼莫艦長的「鸚鵡螺」號送到抵禦的最前線—義大利的威尼斯。那裡有個戴著面具、如鬼魅般的狂人費登，正盤算著要在集合全球領袖的高峰會議上搞鬼，埋設炸彈造成爆炸，把整個城市擊沈。後果將十分慘重，而「不凡紳士聯盟」只有9個小時來拯救世界.....。
In the midst of World War II, Sherlock Holmes rescues the Swiss inventor of a new bomb-sight from the Gestapo and brings him to England, where he quickly falls into the clutches of the evil Professor Moriarty.
Whitechapel, the slums of the East End in London, are being terrorized by a brutal serial killer called Jack the Ripper. While William James Moriarty receives a letter of request from his old teacher Jack Renfield, the Scotland Yard inspector Lestrade also seeks out Sherlock Holmes and John H. Watson for help in this matter.
William James Moriarty and Sherlock Holmes both become entangled with the ruthless "blackmailing king", Charles Augustus Milverton. Both determined to deal with him, Sherlock finally comes face to face with the mystery he's chased and longed for: the Lord of Crime.
William James Moriarty, now known as the "Lord of Crime" to the public, and his allies are still working towards an ideal country by punishing the corrupt nobility. One day the government branch MI6, led by his brother Albert, is given the mission to eliminate a woman called Irene Adler for stealing confidential documents. In the meantime, Adler makes contact with Sherlock Holmes, who has become captivated by the mystery of the Lord of Crime.
At the end of the 19th century, the young mathematics professor William James Moriarty and his allies have decided to take on the British Empire in an effort to destroy the discriminatory class system and create an ideal country. During one of their missions to deliver punishment to the corrupt nobility, William meets a peculiar and intriguing consulting detective named Sherlock Holmes.